Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway - Li, Yujia; Chen, Hui; Yang, Qi; Wan, Lixin; Zhao, Jing; Wu, Yuanyuan; Wang, Jiaxin; Yang, Yating; Niu, Menglan; Liu, Hongliang; Liu, Junqi; Yang, Hushan; et al. (Journal of experimental & clinical cancer research, 2022)
Keywords: Animals; Autophagy; Cell Line, Tumor; Cell Proliferation; cGAS-STING signaling pathway; Development and progression; Disease Progression; DNA, Mitochondrial - pharmacology; DNA, Mitochondrial - therapeutic use; Drp1; Dynamins - metabolism; Esophageal cancer; Esophageal Squamous Cell Carcinoma; Female; Humans; Immune response; Medical research; Medicine, Experimental; Mice; Mice, Knockout; Mice, Nude; Mitochondrial DNA; Mitochondrial DNA stress; Nucleotidyltransferases - metabolism; Photographic industry; Physiological aspects; Squamous cell carcinoma; Japan; Mitochondrial DNA stress; cGAS-STING signaling pathway; Autophagy; Drp1; Esophageal Squamous Cell Carcinoma