Outcomes of a Bladder Cancer Screening Program Using Home Hematuria Testing and Molecular Markers

• Published in: European urology Vol. 64; no. 1; pp. 41 - 47
• Main Authors: Bangma, Chris H., Loeb, Stacy, Busstra, Martijn, Zhu, Xiaoye, El Bouazzaoui, Samira, Refos, Jeanine, Van Der Keur, Kirstin A., Tjin, Stephen, Franken, Conja G.A.M., van Leenders, Geert J.L.H., Zwarthoff, Ellen C., Roobol, Monique J.
• Format: Journal Article
• Language: English
• Published: Kidlington Elsevier B.V 01.07.2013; Elsevier
• Subjects: Aged; Biological and medical sciences; Biomarkers - urine; Bladder cancer; Chi-Square Distribution; Cystoscopy; DNA Methylation; Feasibility Studies; Genetic Markers; Genetic Testing - instrumentation; Hematuria; Hematuria - diagnosis; Hematuria - etiology; Hematuria - genetics; Humans; Male; Mass Screening - instrumentation; Mass Screening - methods; Medical sciences; Microsatellite Instability; Middle Aged; Nephrology. Urinary tract diseases; Netherlands; NMP22, FGFR3, cystoscopy; Nuclear Proteins - urine; Patient Selection; Predictive Value of Tests; Prognosis; Reagent Strips; Receptor, Fibroblast Growth Factor, Type 3 - genetics; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Screening; Self Care - instrumentation; Tumors of the urinary system; Unnecessary Procedures; Urinalysis - instrumentation; Urinary Bladder Neoplasms - complications; Urinary Bladder Neoplasms - diagnosis; Urinary Bladder Neoplasms - genetics; Urinary Bladder Neoplasms - urine; Urinary system involvement in other diseases. Miscellaneous; Urinary tract. Prostate gland; Urology; Netherlands; Screening; Hematuria; NMP22, FGFR3, cystoscopy; Bladder cancer; Nephrology; Urinary system disease; Program; Prognosis; Genetic marker; Cystoscopy; Urinary tract disease; Malignant tumor; Molecular marker; Medical screening; Hemorrhage; Urology; Bladder disease; Cancer; Fibroblast growth factor receptor 3

We previously reported the preliminary findings from a feasibility study of bladder cancer (BCa) screening with urinary molecular markers (Bladder Cancer Urine Marker Project [BLU-P]) that has now been terminated. To report the final results from BLU-P to determine whether mass screening for BCa is...