Uncoordinated expression of DNA methylation-related enzymes in human cancer

• Published in: Epigenetics & chromatin Vol. 10; no. 1; pp. 61 - 9
• Main Authors: Liu, Jiao, Cui, Xiuliang, Jiang, Jinhua, Cao, Dan, He, Yufei, Wang, Hongyang
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 12.12.2017; BioMed Central; BMC
• Subjects: 5mC; 5mC oxidation derivatives; Cancer; Cancer genetics; Correlation; DNA; DNA methylation-related enzymes; Epigenetic inheritance; Gene expression; Genes; Genomes; Genomics; Methylation; Methyltransferases; Physiological aspects; Pyrimidines; DNA methylation-related enzymes; Correlation; 5mC; 5mC oxidation derivatives

In addition to the important roles played by 5-methylcytosine (5mC), emerging evidence suggests that 5mC derivatives, such as 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC), also exhibit regulatory functions in physiological and pathological processes. Four cyto...