Tetrapyrrole biosynthetic enzyme protoporphyrinogen IX oxidase 1 is required for plastid RNA editing

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 111; no. 5; pp. 2023 - 2028
• Main Authors: Zhang, Fan, Tang, Weijiang, Hedtke, Boris, Zhong, Linlin, Liu, Lin, Peng, Lianwei, Lu, Congming, Grimm, Bernhard, Lin, Rongcheng
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 04.02.2014; National Acad Sciences
• Subjects: Amino acids; Arabidopsis - enzymology; Arabidopsis - genetics; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Arabidopsis thaliana; Base Sequence; Biological Sciences; Biosynthesis; Chlorophyll - biosynthesis; Chlorophylls; Enzymes; Flavin-Adenine Dinucleotide - metabolism; Flowering plants; Genetic engineering; Molecular Sequence Data; NADH Dehydrogenase - metabolism; Phenotype; Plants; Plastids; Plastids - enzymology; Plastids - genetics; Protein Binding; Proteins; Protoporphyrinogen Oxidase - genetics; Protoporphyrinogen Oxidase - metabolism; Ribonucleic acid; RNA; RNA editing; RNA Editing - genetics; Seedlings - growth & development; Substrate Specificity; Synthetic biology; Tetrapyrroles; Tetrapyrroles - biosynthesis; Transgenic plants; organelle; metabolism; editosome

RNA editing is a posttranscriptional process that covalently alters the sequence of RNA molecules and plays important biological roles in both animals and land plants. In flowering plants, RNA editing converts specific cytidine residues to uridine in both plastid and mitochondrial transcripts. Previ...