Placenta Accreta Spectrum: A Review of Pathology, Molecular Biology, and Biomarkers

• Published in: Disease markers Vol. 2018; no. 2018; pp. 1 - 11
• Main Authors: Brennan, Donal J., Downey, Paul, Postle, James D., Bartels, Helena C.
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2018; Hindawi; John Wiley & Sons, Inc
• Subjects: Angiogenesis; Bioindicators; Biological markers; Biology; Biomarkers; Biomarkers - blood; Blood proteins; Chorionic gonadotropin; Decidua; Diagnosis; Diagnostic systems; Female; Fetal Proteins - blood; Fibers; Gestational age; Glycoproteins; Gonadotropins; Gonadotropins - blood; Gynecology; Health aspects; Humans; Maternal mortality; Molecular biology; Molecular chains; Morbidity; Myometrium; Obstetrics; Pathology; Pituitary (anterior); Placenta; Placenta Accreta - blood; Placenta Accreta - metabolism; Placenta Accreta - pathology; Plasma; Preeclampsia; Pregnancy; Pregnancy complications; Pregnancy-Associated Plasma Protein-A - metabolism; Prenatal development; Proteins; Review; Vascular endothelial growth factor; α-Fetoprotein; United Kingdom > UK
• ISSN: 0278-0240; 1875-8630; 1875-8630
• DOI: 10.1155/2018/1507674

Background. Placenta accreta spectrum (PAS) is a condition of abnormal placental invasion encompassing placenta accreta, increta, and percreta and is a major cause of severe maternal morbidity and mortality. The diagnosis of a PAS is made on the basis of histopathologic examination and characterised...