Dietary Flaxseed Oil Prevents Western-Type Diet-Induced Nonalcoholic Fatty Liver Disease in Apolipoprotein-E Knockout Mice

• Published in: Oxidative medicine and cellular longevity Vol. 2017; no. 2017; pp. 1 - 13
• Main Authors: Li, Xiuhua, Tang, Haiying, Zhao, Haifeng, Qiu, Fubin, Han, Hao, Shi, Dongxing
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2017; Hindawi; John Wiley & Sons, Inc
• Subjects: Animals; Apolipoproteins; Apolipoproteins E - metabolism; Care and treatment; Cholesterol; Cytokines; Development and progression; Diet; Fatty acids; Fatty liver; Fish oils; Flaxseed oil; Food; Gastroenterology; Genetic aspects; Health aspects; Hepatology; Laboratory animals; Linseed Oil - chemistry; Lipids; Liver diseases; Male; Mice; Non-alcoholic Fatty Liver Disease - pathology; Non-alcoholic Fatty Liver Disease - prevention & control; Nutrition research; Oils & fats; Polyunsaturated fatty acids; Rodents; China

The prevalence of nonalcoholic fatty liver disease (NAFLD) has dramatically increased globally during recent decades. Intake of n-3 polyunsaturated fatty acids (PUFAs), mainly eicosapentaenoic acid (EPA, C20:5n-3) and docosahexaenoic acid (DHA, C22:6n-3), is believed to be beneficial to the developm...