Individual-specific functional connectivity markers track dimensional and categorical features of psychotic illness

• Published in: Molecular psychiatry Vol. 25; no. 9; pp. 2119 - 2129
• Main Authors: Wang, Danhong, Li, Meiling, Wang, Meiyun, Schoeppe, Franziska, Ren, Jianxun, Chen, Huafu, Öngür, Dost, Brady, Roscoe O., Baker, Justin T., Liu, Hesheng
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.09.2020; Nature Publishing Group
• Subjects: 59/36; 631/378; 692/699/476/1333; 692/699/476/1799; Anatomy; Behavioral Sciences; Biological Psychology; Biomarkers; Bipolar Disorder; Brain architecture; Care and treatment; Development and progression; Emotional behavior; Etiology; Health aspects; Humans; Magnetic Resonance Imaging; Mania; Medical imaging; Medical research; Medicine; Medicine & Public Health; Medicine, Experimental; Mental disorders; Neural networks; Neuroimaging; Neurosciences; Patients; Pharmacotherapy; Psychiatry; Psychosis; Psychotic Disorders - diagnostic imaging; Schizoaffective disorder; Schizophrenia; Schizophrenia - diagnostic imaging; Structure-function relationships

Neuroimaging studies of psychotic disorders have demonstrated abnormalities in structural and functional connectivity involving widespread brain networks. However, these group-level observations have failed to yield any biomarkers that can provide confirmatory evidence of a patient’s current symptom...