Effects of human herpesvirus 6B reactivation on cognitive function in cord blood transplant recipients: a prospective multicenter study

• Published in: International journal of hematology Vol. 119; no. 4; pp. 432 - 441
• Main Authors: Ogata, Masao, Oshima, Kumi, Takano, Kuniko, Kawano, Rie, Ueda, Yasunori, Imamura, Takashi, Nakamura, Yukinori, Okada, Takahiro, Toubai, Tomomi, Ueki, Toshimitsu, Uoshima, Nobuhiko, Ishida, Hiroyuki, Shinohara, Akihito, Seo, Sachiko, Fukuda, Takahiro, Inagaki, Masatoshi
• Format: Journal Article
• Language: English
• Published: Singapore Springer Nature Singapore 01.04.2024; Springer Nature B.V
• Subjects: Blood; Central nervous system; Cognition; Cognitive ability; Cord blood; Cord Blood Stem Cell Transplantation - adverse effects; Delirium; DNA, Viral; Hematology; Hematopoietic Stem Cell Transplantation; Herpes viruses; Herpesvirus 6, Human - genetics; Humans; Information processing; Medicine; Medicine & Public Health; Memory; Mental disorders; Oncology; Original; Original Article; Preconditioning; Prospective Studies; Quality of Life; Transplantation; Transplants & implants; Virus Activation; Human herpesvirus-6B; Cognitive function; Memory function; Cord blood transplantation

This prospective multicenter study aimed to determine the effects of human herpesvirus-6B (HHV-6B) reactivation on central nervous system (CNS) function in cord blood transplant (CBT) recipients. Our focus was to track HHV-6B reactivation and evaluate its association with delirium and cognitive func...