Differential Expression of Glycolysis-Related Proteins in Follicular Neoplasms versus Hürthle Cell Neoplasms: A Retrospective Analysis

• Published in: Disease markers Vol. 2017; no. 2017; pp. 1 - 10
• Main Authors: Kim, Hye Min, Koo, Ja Seung
• Format: Journal Article
• Language: English
• Published: Cairo, Egypt Hindawi Publishing Corporation 01.01.2017; Hindawi; John Wiley & Sons, Inc; Hindawi Limited
• Subjects: Adenoma - genetics; Adenoma - metabolism; Adenoma, Oxyphilic - genetics; Adenoma, Oxyphilic - metabolism; Cancer; Carbonic Anhydrase IX - genetics; Carbonic Anhydrase IX - metabolism; Carcinoma; Carcinoma - genetics; Carcinoma - metabolism; Comparative analysis; Female; Gene expression; Genetic aspects; Glucose Transporter Type 1 - genetics; Glucose Transporter Type 1 - metabolism; Glycolysis; Hexokinase; Hexokinase - genetics; Hexokinase - metabolism; Humans; Male; Metabolism; Middle Aged; Monocarboxylic Acid Transporters - genetics; Monocarboxylic Acid Transporters - metabolism; Muscle Proteins - genetics; Muscle Proteins - metabolism; Neoplasia; Neoplasms; Proteins; Thyroid cancer; Thyroid Neoplasms - genetics; Thyroid Neoplasms - metabolism; Tumors

Purpose. Although currently classified as variants of follicular neoplasms (FNs), Hürthle cell neoplasms (HCNs) exhibit distinct biological characteristics. Hence, the metabolism of both neoplasms may also be different. The aims of this study were to investigate and compare the expression of glycoly...