Definite intensity-modulated radiotherapy with concurrent chemotherapy more than 4 cycles improved survival for patients with locally-advanced or inoperable esophageal squamous cell carcinoma

• Published in: The Kaohsiung journal of medical sciences Vol. 34; no. 5; pp. 281 - 289
• Main Authors: Hsieh, He-Yuan, Hsu, Chung-Ping, Yeh, Hui-Ling, Chuang, Cheng-Yen, Lin, Jai-Fu, Chang, Chen-Fa
• Format: Journal Article
• Language: English
• Published: China (Republic : 1949- ) Elsevier Taiwan 01.05.2018; Wiley
• Subjects: Adult; Aged; Aged, 80 and over; Antineoplastic Agents - therapeutic use; Carcinoma, Squamous Cell - diagnosis; Carcinoma, Squamous Cell - mortality; Carcinoma, Squamous Cell - pathology; Carcinoma, Squamous Cell - therapy; Chemoradiotherapy; Chemoradiotherapy - methods; Cisplatin - therapeutic use; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Administration Schedule; Esophageal neoplasms; Esophageal Neoplasms - diagnosis; Esophageal Neoplasms - mortality; Esophageal Neoplasms - pathology; Esophageal Neoplasms - therapy; Esophageal Squamous Cell Carcinoma; Female; Fluorouracil - therapeutic use; Follow-Up Studies; Gamma Rays - therapeutic use; Humans; Male; Middle Aged; Neoplasm Staging; Prognosis; Retrospective Studies; Squamous cell carcinoma; Survival Analysis; Chemoradiotherapy; Squamous cell carcinoma; Esophageal neoplasms

We investigated which prognostic factor could improve survival for esophageal cancer patients who received definite concurrent chemoradiation (CCRT). Eighty patients with age ≥18, Karnofsky Performance Scale (KPS) ≥ 60, and clinical stage T1-4N0-3M0 esophageal squamous cell carcinoma were enrolled f...