Lumbar puncture in pediatric bacterial meningitis: defining the time interval for recovery of cerebrospinal fluid pathogens after parenteral antibiotic pretreatment

• Published in: Pediatrics (Evanston) Vol. 108; no. 5; p. 1169
• Main Authors: Kanegaye, J T, Soliemanzadeh, P, Bradley, J S
• Format: Journal Article
• Language: English
• Published: United States 01.11.2001
• Subjects: Adolescent; Anti-Bacterial Agents - therapeutic use; Cefotaxime - therapeutic use; Ceftriaxone - therapeutic use; Child; Child, Preschool; Confidence Intervals; Female; Humans; Infant; Infant, Newborn; Male; Meningitis, Bacterial - cerebrospinal fluid; Meningitis, Bacterial - drug therapy; Meningitis, Bacterial - microbiology; Meningitis, Haemophilus - cerebrospinal fluid; Meningitis, Haemophilus - drug therapy; Meningitis, Meningococcal - cerebrospinal fluid; Meningitis, Meningococcal - drug therapy; Meningitis, Pneumococcal - cerebrospinal fluid; Meningitis, Pneumococcal - drug therapy; Patient Selection; Spinal Puncture; Time Factors

Despite the lack of evidence defining a time interval during which cerebrospinal fluid (CSF) culture yield will not be affected by previous antibiotic therapy, recent publications cite a "minimum window" of 2 to 3 hours for recovery of bacterial pathogens after parenteral antibiotic admini...