A comparative study of two methods of optic disc evaluation in patients of glaucoma
Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. Objective: The objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with...
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Published in | Oman journal of ophthalmology Vol. 6; no. 2; pp. 103 - 107 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
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India
Medknow Publications
01.05.2013
Medknow Publications and Media Pvt. Ltd Medknow Publications & Media Pvt. Ltd Medknow Publications & Media Pvt Ltd Wolters Kluwer Medknow Publications |
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Abstract | Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy.
Objective: The objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with retinal nerve fiber layer (RNFL) and global indices in Humphrey field analyzer II (HFA II).
Design: Cross-sectional study.
Materials and Methods: A total of 50 patients diagnosed with primary open angle glaucoma were examined to grade DDLS score and C/D ratio. The average (avg) RNFL was obtained using the Fast RNFL protocol on optical coherence tomography (OCT) (4.0.2 Carl Zeiss). HFA II Swedish Interactive Threshold Algorithm Standard 24-2 visual fields were obtained within 1 month of clinical examination. The correlation of C/D ratio with avg RNFL thickness, Mean deviation and Pattern standard deviation was calculated by Pearson correlation coefficient (r). Similar coefficients were obtained for DDLS.
Results: The P value for the difference in the r between C/D ratio with RNFL (−0.628) and DDLS with RNFL (−0.8369) was significant (P < 0.01) when correlation of C/D, DDLS with RNFL was considered.
Conclusion: The DDLS shows stronger correlation with structural changes in OCT than C/D ratio. The disc diameter and rim width increases the value of clinical optic disc examination. |
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AbstractList | INTRODUCTIONGlaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. OBJECTIVEThe objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with retinal nerve fiber layer (RNFL) and global indices in Humphrey field analyzer II (HFA II). DESIGNCross-sectional study. MATERIALS AND METHODSA total of 50 patients diagnosed with primary open angle glaucoma were examined to grade DDLS score and C/D ratio. The average (avg) RNFL was obtained using the Fast RNFL protocol on optical coherence tomography (OCT) (4.0.2 Carl Zeiss). HFA II Swedish Interactive Threshold Algorithm Standard 24-2 visual fields were obtained within 1 month of clinical examination. The correlation of C/D ratio with avg RNFL thickness, Mean deviation and Pattern standard deviation was calculated by Pearson correlation coefficient (r). Similar coefficients were obtained for DDLS. RESULTSThe P value for the difference in the r between C/D ratio with RNFL (-0.628) and DDLS with RNFL (-0.8369) was significant (P < 0.01) when correlation of C/D, DDLS with RNFL was considered. CONCLUSIONThe DDLS shows stronger correlation with structural changes in OCT than C/D ratio. The disc diameter and rim width increases the value of clinical optic disc examination. Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. The objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with retinal nerve fiber layer (RNFL) and global indices in Humphrey field analyzer II (HFA II). Cross-sectional study. A total of 50 patients diagnosed with primary open angle glaucoma were examined to grade DDLS score and C/D ratio. The average (avg) RNFL was obtained using the Fast RNFL protocol on optical coherence tomography (OCT) (4.0.2 Carl Zeiss). HFA II Swedish Interactive Threshold Algorithm Standard 24-2 visual fields were obtained within 1 month of clinical examination. The correlation of C/D ratio with avg RNFL thickness, Mean deviation and Pattern standard deviation was calculated by Pearson correlation coefficient (r). Similar coefficients were obtained for DDLS. The P value for the difference in the r between C/D ratio with RNFL (-0.628) and DDLS with RNFL (-0.8369) was significant (P < 0.01) when correlation of C/D, DDLS with RNFL was considered. The DDLS shows stronger correlation with structural changes in OCT than C/D ratio. The disc diameter and rim width increases the value of clinical optic disc examination. Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. Objective: The objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with retinal nerve fiber layer (RNFL) and global indices in Humphrey field analyzer II (HFA II). Design: Cross-sectional study. Materials and Methods: A total of 50 patients diagnosed with primary open angle glaucoma were examined to grade DDLS score and C/D ratio. The average (avg) RNFL was obtained using the Fast RNFL protocol on optical coherence tomography (OCT) (4.0.2 Carl Zeiss). HFA II Swedish Interactive Threshold Algorithm Standard 24-2 visual fields were obtained within 1 month of clinical examination. The correlation of C/D ratio with avg RNFL thickness, Mean deviation and Pattern standard deviation was calculated by Pearson correlation coefficient (r). Similar coefficients were obtained for DDLS. Results: The P value for the difference in the r between C/D ratio with RNFL (−0.628) and DDLS with RNFL (−0.8369) was significant (P < 0.01) when correlation of C/D, DDLS with RNFL was considered. Conclusion: The DDLS shows stronger correlation with structural changes in OCT than C/D ratio. The disc diameter and rim width increases the value of clinical optic disc examination. Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. Objective: The objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with retinal nerve fiber layer (RNFL) and global indices in Humphrey field analyzer II (HFA II). Design: Cross-sectional study. Materials and Methods: A total of 50 patients diagnosed with primary open angle glaucoma were examined to grade DDLS score and C/D ratio. The average (avg) RNFL was obtained using the Fast RNFL protocol on optical coherence tomography (OCT) (4.0.2 Carl Zeiss). HFA II Swedish Interactive Threshold Algorithm Standard 24-2 visual fields were obtained within 1 month of clinical examination. The correlation of C/D ratio with avg RNFL thickness, Mean deviation and Pattern standard deviation was calculated by Pearson correlation coefficient (r). Similar coefficients were obtained for DDLS. Results: The P value for the difference in the r between C/D ratio with RNFL (−0.628) and DDLS with RNFL (−0.8369) was significant (P < 0.01) when correlation of C/D, DDLS with RNFL was considered. Conclusion: The DDLS shows stronger correlation with structural changes in OCT than C/D ratio. The disc diameter and rim width increases the value of clinical optic disc examination. Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. Objective: The objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with retinal nerve fiber layer (RNFL) and global indices in Humphrey field analyzer II (HFA II). Design: Cross-sectional study. Materials and Methods: A total of 50 patients diagnosed with primary open angle glaucoma were examined to grade DDLS score and C/D ratio. The average (avg) RNFL was obtained using the Fast RNFL protocol on optical coherence tomography (OCT) (4.0.2 Carl Zeiss). HFA II Swedish Interactive Threshold Algorithm Standard 24-2 visual fields were obtained within 1 month of clinical examination. The correlation of C/D ratio with avg RNFL thickness, Mean deviation and Pattern standard deviation was calculated by Pearson correlation coefficient (r). Similar coefficients were obtained for DDLS. Results: The P value for the difference in the r between C/D ratio with RNFL (-0.628) and DDLS with RNFL (-0.8369) was significant (P < 0.01) when correlation of C/D, DDLS with RNFL was considered. Conclusion: The DDLS shows stronger correlation with structural changes in OCT than C/D ratio. The disc diameter and rim width increases the value of clinical optic disc examination. |
Audience | Academic |
Author | Chandra, Anuradha Bandyopadhyay, Arun Bhaduri, Gautam |
AuthorAffiliation | 2 Regional Institute of Ophthalmology, Medical College Kolkata, Kolkata, West Bengal, India 1 Department of Ophthalmology, Burdwan Medical College, Kolkata, West Bengal, India Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India |
AuthorAffiliation_xml | – name: Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India – name: 1 Department of Ophthalmology, Burdwan Medical College, Kolkata, West Bengal, India – name: 2 Regional Institute of Ophthalmology, Medical College Kolkata, Kolkata, West Bengal, India |
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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/24082669$$D View this record in MEDLINE/PubMed |
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Copyright | COPYRIGHT 2013 Medknow Publications and Media Pvt. Ltd. Copyright Medknow Publications & Media Pvt Ltd May 2013 Copyright: © 2013 Chandra A, . 2013 |
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Keywords | disc damage likelihood scale visual field retinal nerve fiber layer thickness Cup/disc ratio |
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References_xml | – start-page: 44 volume-title: Reliability of the disk damage likelihood scale year: 2003 ident: key-10.4103/0974-620X.116643-11 publication-title: Am J Ophthalmol contributor: fullname: Henderer – start-page: 827 volume-title: Comparison of the GDx VCC scanning laser polarimeter, HRT II confocal scanning laser ophthalmoscope, and stratus OCT optical coherence tomograph for the detection of glaucoma year: 2004 ident: key-10.4103/0974-620X.116643-18 publication-title: Arch Ophthalmol contributor: fullname: Medeiros – start-page: 437 volume-title: Comparison of disc damage likelihood scale, cup to disc ratio, and Heidelberg retina tomograph in the diagnosis of glaucoma.Br J Ophthalmol year: 2006 ident: key-10.4103/0974-620X.116643-6 contributor: fullname: Danesh-Meyer – start-page: 2242 volume-title: Ganglion cell losses underlying visual field defects from experimental glaucoma year: 1999 ident: key-10.4103/0974-620X.116643-15 publication-title: Invest Ophthalmol Vis Sci contributor: fullname: Harwerth – start-page: 153 volume-title: Discrimination between normal and glaucomatous eyes year: 1992 ident: key-10.4103/0974-620X.116643-7 publication-title: Invest Ophthalmol Vis Sci contributor: fullname: Caprioli – start-page: 587 volume-title: Nerve fiber layer defects with normal visual fields.Do normal optic disc and normal visual field indicate absence of glaucomatous abnormality? 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Snippet | Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy.
Objective: The... Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. The objective of this study was... Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. Objective: The... INTRODUCTIONGlaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. OBJECTIVEThe... |
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StartPage | 103 |
SubjectTerms | Comparative studies Cup/disc ratio Development and progression disc damage likelihood scale Glaucoma Health aspects Medical examination Methods Ophthalmology Optic disc Original retinal nerve fiber layer thickness Risk factors visual field |
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Title | A comparative study of two methods of optic disc evaluation in patients of glaucoma |
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