A comparative study of two methods of optic disc evaluation in patients of glaucoma

Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. Objective: The objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with...

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Published inOman journal of ophthalmology Vol. 6; no. 2; pp. 103 - 107
Main Authors Chandra, Anuradha, Bandyopadhyay, Arun, Bhaduri, Gautam
Format Journal Article
LanguageEnglish
Published India Medknow Publications 01.05.2013
Medknow Publications and Media Pvt. Ltd
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Medknow Publications & Media Pvt Ltd
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Abstract Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. Objective: The objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with retinal nerve fiber layer (RNFL) and global indices in Humphrey field analyzer II (HFA II). Design: Cross-sectional study. Materials and Methods: A total of 50 patients diagnosed with primary open angle glaucoma were examined to grade DDLS score and C/D ratio. The average (avg) RNFL was obtained using the Fast RNFL protocol on optical coherence tomography (OCT) (4.0.2 Carl Zeiss). HFA II Swedish Interactive Threshold Algorithm Standard 24-2 visual fields were obtained within 1 month of clinical examination. The correlation of C/D ratio with avg RNFL thickness, Mean deviation and Pattern standard deviation was calculated by Pearson correlation coefficient (r). Similar coefficients were obtained for DDLS. Results: The P value for the difference in the r between C/D ratio with RNFL (−0.628) and DDLS with RNFL (−0.8369) was significant (P < 0.01) when correlation of C/D, DDLS with RNFL was considered. Conclusion: The DDLS shows stronger correlation with structural changes in OCT than C/D ratio. The disc diameter and rim width increases the value of clinical optic disc examination.
AbstractList INTRODUCTIONGlaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. OBJECTIVEThe objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with retinal nerve fiber layer (RNFL) and global indices in Humphrey field analyzer II (HFA II). DESIGNCross-sectional study. MATERIALS AND METHODSA total of 50 patients diagnosed with primary open angle glaucoma were examined to grade DDLS score and C/D ratio. The average (avg) RNFL was obtained using the Fast RNFL protocol on optical coherence tomography (OCT) (4.0.2 Carl Zeiss). HFA II Swedish Interactive Threshold Algorithm Standard 24-2 visual fields were obtained within 1 month of clinical examination. The correlation of C/D ratio with avg RNFL thickness, Mean deviation and Pattern standard deviation was calculated by Pearson correlation coefficient (r). Similar coefficients were obtained for DDLS. RESULTSThe P value for the difference in the r between C/D ratio with RNFL (-0.628) and DDLS with RNFL (-0.8369) was significant (P < 0.01) when correlation of C/D, DDLS with RNFL was considered. CONCLUSIONThe DDLS shows stronger correlation with structural changes in OCT than C/D ratio. The disc diameter and rim width increases the value of clinical optic disc examination.
Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. The objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with retinal nerve fiber layer (RNFL) and global indices in Humphrey field analyzer II (HFA II). Cross-sectional study. A total of 50 patients diagnosed with primary open angle glaucoma were examined to grade DDLS score and C/D ratio. The average (avg) RNFL was obtained using the Fast RNFL protocol on optical coherence tomography (OCT) (4.0.2 Carl Zeiss). HFA II Swedish Interactive Threshold Algorithm Standard 24-2 visual fields were obtained within 1 month of clinical examination. The correlation of C/D ratio with avg RNFL thickness, Mean deviation and Pattern standard deviation was calculated by Pearson correlation coefficient (r). Similar coefficients were obtained for DDLS. The P value for the difference in the r between C/D ratio with RNFL (-0.628) and DDLS with RNFL (-0.8369) was significant (P < 0.01) when correlation of C/D, DDLS with RNFL was considered. The DDLS shows stronger correlation with structural changes in OCT than C/D ratio. The disc diameter and rim width increases the value of clinical optic disc examination.
Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. Objective: The objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with retinal nerve fiber layer (RNFL) and global indices in Humphrey field analyzer II (HFA II). Design: Cross-sectional study. Materials and Methods: A total of 50 patients diagnosed with primary open angle glaucoma were examined to grade DDLS score and C/D ratio. The average (avg) RNFL was obtained using the Fast RNFL protocol on optical coherence tomography (OCT) (4.0.2 Carl Zeiss). HFA II Swedish Interactive Threshold Algorithm Standard 24-2 visual fields were obtained within 1 month of clinical examination. The correlation of C/D ratio with avg RNFL thickness, Mean deviation and Pattern standard deviation was calculated by Pearson correlation coefficient (r). Similar coefficients were obtained for DDLS. Results: The P value for the difference in the r between C/D ratio with RNFL (−0.628) and DDLS with RNFL (−0.8369) was significant (P < 0.01) when correlation of C/D, DDLS with RNFL was considered. Conclusion: The DDLS shows stronger correlation with structural changes in OCT than C/D ratio. The disc diameter and rim width increases the value of clinical optic disc examination.
Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. Objective: The objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with retinal nerve fiber layer (RNFL) and global indices in Humphrey field analyzer II (HFA II). Design: Cross-sectional study. Materials and Methods: A total of 50 patients diagnosed with primary open angle glaucoma were examined to grade DDLS score and C/D ratio. The average (avg) RNFL was obtained using the Fast RNFL protocol on optical coherence tomography (OCT) (4.0.2 Carl Zeiss). HFA II Swedish Interactive Threshold Algorithm Standard 24-2 visual fields were obtained within 1 month of clinical examination. The correlation of C/D ratio with avg RNFL thickness, Mean deviation and Pattern standard deviation was calculated by Pearson correlation coefficient (r). Similar coefficients were obtained for DDLS. Results: The P value for the difference in the r between C/D ratio with RNFL (−0.628) and DDLS with RNFL (−0.8369) was significant (P < 0.01) when correlation of C/D, DDLS with RNFL was considered. Conclusion: The DDLS shows stronger correlation with structural changes in OCT than C/D ratio. The disc diameter and rim width increases the value of clinical optic disc examination.
Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. Objective: The objective of this study was to determine the correlation between each of cup/disc (C/D) ratio and the disc damage likelihood scale (DDLS) with retinal nerve fiber layer (RNFL) and global indices in Humphrey field analyzer II (HFA II). Design: Cross-sectional study. Materials and Methods: A total of 50 patients diagnosed with primary open angle glaucoma were examined to grade DDLS score and C/D ratio. The average (avg) RNFL was obtained using the Fast RNFL protocol on optical coherence tomography (OCT) (4.0.2 Carl Zeiss). HFA II Swedish Interactive Threshold Algorithm Standard 24-2 visual fields were obtained within 1 month of clinical examination. The correlation of C/D ratio with avg RNFL thickness, Mean deviation and Pattern standard deviation was calculated by Pearson correlation coefficient (r). Similar coefficients were obtained for DDLS. Results: The P value for the difference in the r between C/D ratio with RNFL (-0.628) and DDLS with RNFL (-0.8369) was significant (P < 0.01) when correlation of C/D, DDLS with RNFL was considered. Conclusion: The DDLS shows stronger correlation with structural changes in OCT than C/D ratio. The disc diameter and rim width increases the value of clinical optic disc examination.
Audience Academic
Author Chandra, Anuradha
Bandyopadhyay, Arun
Bhaduri, Gautam
AuthorAffiliation 2 Regional Institute of Ophthalmology, Medical College Kolkata, Kolkata, West Bengal, India
1 Department of Ophthalmology, Burdwan Medical College, Kolkata, West Bengal, India
Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/24082669$$D View this record in MEDLINE/PubMed
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Copyright COPYRIGHT 2013 Medknow Publications and Media Pvt. Ltd.
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Issue 2
Keywords disc damage likelihood scale
visual field
retinal nerve fiber layer thickness
Cup/disc ratio
Language English
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Snippet Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. Objective: The...
Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. The objective of this study was...
Introduction: Glaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. Objective: The...
INTRODUCTIONGlaucoma is a progressive disorder and requires serial evaluation in order to monitor disease progression and optimize therapy. OBJECTIVEThe...
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StartPage 103
SubjectTerms Comparative studies
Cup/disc ratio
Development and progression
disc damage likelihood scale
Glaucoma
Health aspects
Medical examination
Methods
Ophthalmology
Optic disc
Original
retinal nerve fiber layer thickness
Risk factors
visual field
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Title A comparative study of two methods of optic disc evaluation in patients of glaucoma
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