Genome-wide analysis study of gestational diabetes mellitus and related pathogenic factors in a Chinese Han population

• Published in: BMC pregnancy and childbirth Vol. 23; no. 1; pp. 856 - 9
• Main Authors: Yue, Shufan, Pei, Ling, Lai, Fenghua, Xiao, Huangmeng, Li, Zeting, Zeng, Rui, Chen, Li, Chen, Wenzhan, Liu, Huiling, Li, Yanbing, Xiao, Haipeng, Cao, Xiaopei
• Format: Journal Article
• Language: English
• Published: England BioMed Central 12.12.2023; BMC
• Subjects: Blood Glucose - metabolism; Body mass index; Deoxyribonucleic acid; Diabetes, Gestational - epidemiology; DNA; Ethnicity; Female; Genes; Genome-Wide Association Study; Genomes; Gestational diabetes; Gestational Diabetes Mellitus; Glucose; Glucose - metabolism; GWAS; Humans; Insulin resistance; Insulin Resistance - genetics; Metabolism; Nuclear Proteins - genetics; Obesity; Plasma; Polymorphism, Single Nucleotide; Pregnancy; Protein-Arginine N-Methyltransferases - genetics; Quality control; Regression analysis; SNP; Susceptibility gene; Womens health; United States > US; China; Gestational Diabetes Mellitus; GWAS; SNP; Susceptibility gene

Gestational diabetes mellitus (GDM) affects the metabolism of both the mother and fetus during and after pregnancy. Genetic factors are important in the pathogenesis of GDM, and associations vary by ethnicity. However, related studies about the relationship between the susceptibility genes and gluco...