Tofogliflozin long-term effects on atherosclerosis progression and major clinical parameters in patients with type 2 diabetes mellitus lacking a history of cardiovascular disease: a 2-year extension study of the UTOPIA trial - Katakami, Naoto; Mita, Tomoya; Yoshii, Hidenori; Shiraiwa, Toshihiko; Yasuda, Tetsuyuki; Okada, Yosuke; Kurozumi, Akira; Hatazaki, Masahiro; Kaneto, Hideaki; Osonoi, Takeshi; Yamamoto, Tsunehiko; Kuribayashi, Nobuichi; et al. (Cardiovascular diabetology, 2023)
Keywords: Ankle; Ankle Brachial Index; Antidiabetics; Arteriosclerosis; Atherosclerosis; Blood pressure; Body mass index; Brachial-ankle pulse wave velocity; Cardiovascular disease; Cardiovascular diseases; Cardiovascular Diseases - diagnosis; Cardiovascular Diseases - drug therapy; Cardiovascular Diseases - prevention & control; Cardiovascular risk factors; Carotid arteries; Carotid artery; Carotid Intima-Media Thickness; Cholesterol; Consent; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - complications; Diabetes Mellitus, Type 2 - diagnosis; Diabetes Mellitus, Type 2 - drug therapy; Drug dosages; Ethics; Glucose; Glucose metabolism; Hemoglobin; High density lipoprotein; Human subjects; Humans; Hypoglycemia; Lipid metabolism; Long-term effects; Medical research; Na+/glucose cotransporter; Patients; Pulse Wave Analysis; Renal function; Review boards; Risk factors; Sodium-glucose cotransporter 2 inhibitor; Tofogliflozin; Utopias; Japan; Tofogliflozin; Sodium-glucose cotransporter 2 inhibitor; Cardiovascular risk factors; Brachial-ankle pulse wave velocity; Atherosclerosis; Carotid intima-media thickness