Exploration of rituximab treatment strategies for membranous nephropathy adapted to the Chinese healthcare environment

• Published in: BMC nephrology Vol. 26; no. 1; pp. 49 - 12
• Main Authors: Wang, Xiaolong, Cao, Xueying, Wu, Jie, Liang, Shuang, Yang, Jian, Wang, Hong
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 31.01.2025; BioMed Central; BMC
• Subjects: Adult; Analysis; B cells; Biopsy; Blood cell count; Cardiovascular disease; Care and treatment; China; Comorbidity; Corticosteroids; Development and progression; Diabetes mellitus; Drug dosages; Drug therapy; Drug Therapy, Combination; Female; Glomerulonephritis, Membranous - drug therapy; Glucocorticoids - therapeutic use; Health aspects; Hepatitis; Humans; Immunologic Factors - therapeutic use; Immunosuppressive agents; Immunosuppressive Agents - therapeutic use; Immunotherapy; Infections; Kidney diseases; Leukocytes; Male; Medical centers; Medical prognosis; Medical research; Medicine, Experimental; Membranous nephropathy; Middle Aged; Monoclonal antibodies; Nephropathy; Patient compliance; Patients; Pharmacology, Experimental; Physiological aspects; Proteins; Recurrence; Regression analysis; Relapse; Remission; Remission (Medicine); Remission Induction; Retrospective Studies; Risk factors; Rituximab; Rituximab - therapeutic use; Statistical analysis; Steroids; Treatment Outcome; Urine; China; Minnesota; Rituximab; Remission; Relapse; Membranous nephropathy

This study aimed to explore the specific efficacy of rituximab (RTX) in the treatment of membranous nephropathy (MN) and compare and analyze the differences in effectiveness among various treatment regimens, with the objective of identifying the optimal treatment protocol suitable for the medical en...