Upregulation of microRNA-137 expression by Slug promotes tumor invasion and metastasis of non-small cell lung cancer cells through suppression of TFAP2C - Chang, Tzu-Hua; Tsai, Meng-Feng; Gow, Chien-Hung; Wu, Shang-Gin; Liu, Yi-Nan; Chang, Yih-Leong; Yu, Sung-Liang; Tsai, Hsing-Chen; Lin, Shih-Wen; Chen, Yen-Wei; Kuo, Po-Yen; Yang, Pan-Chyr; et al. (Cancer letters, 2017)
Keywords: 3' Untranslated Regions; Adenocarcinoma; Adenocarcinoma - genetics; Adenocarcinoma - metabolism; Adenocarcinoma - mortality; Adenocarcinoma - secondary; Adenocarcinoma of Lung; Animals; Antineoplastic Agents - pharmacology; Apoptosis; Arrays; Binding Sites; Biomarkers, Tumor - genetics; Biomarkers, Tumor - metabolism; Carcinoma, Non-Small-Cell Lung - genetics; Carcinoma, Non-Small-Cell Lung - metabolism; Carcinoma, Non-Small-Cell Lung - mortality; Carcinoma, Non-Small-Cell Lung - secondary; Cell cycle; Cell growth; Cell Line, Tumor; Cell Movement - drug effects; Cisplatin - pharmacology; Epithelial-mesenchymal transition (EMT); Gene expression; Gene Expression Regulation, Neoplastic; Hematology, Oncology and Palliative Medicine; Humans; Kaplan-Meier Estimate; Kinases; Lung cancer; Lung Neoplasms - genetics; Lung Neoplasms - metabolism; Lung Neoplasms - mortality; Lung Neoplasms - pathology; Male; Medical prognosis; Mesenchyme; Metastases; Metastasis; Mice, Inbred NOD; Mice, SCID; MicroRNAs; MicroRNAs - genetics; MicroRNAs - metabolism; miR-137; miRNA; Neoplasm Invasiveness; Non-small cell lung cancer (NSCLC); Non-small cell lung carcinoma; Promoter Regions, Genetic; Protein Binding; RNA Interference; Signal Transduction; Slug; Snail Family Transcription Factors - genetics; Snail Family Transcription Factors - metabolism; Survival; TFAP2C; Thyroid cancer; Time Factors; Transcription Factor AP-2 - genetics; Transcription Factor AP-2 - metabolism; Transcription factors; Transfection; Up-Regulation; Epithelial-mesenchymal transition (EMT); miR-137; TFAP2C; Slug; Non-small cell lung cancer (NSCLC)