Ground-glass opacity (GGO): a review of the differential diagnosis in the era of COVID-19

Thoracic imaging is fundamental in the diagnostic route of Coronavirus disease 2019 (COVID-19) especially in patients admitted to hospitals. In particular, chest computed tomography (CT) has a key role in identifying the typical features of the infection. Ground-glass opacities (GGO) are one of the...

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Published in	Japanese journal of radiology Vol. 39; no. 8; pp. 721 - 732
Main Authors	Cozzi, Diletta, Cavigli, Edoardo, Moroni, Chiara, Smorchkova, Olga, Zantonelli, Giulia, Pradella, Silvia, Miele, Vittorio
Format	Journal Article
Language	English
Published	Singapore Springer Singapore 01.08.2021 Springer Nature B.V
Subjects	Computed tomography Coronaviruses COVID-19 COVID-19 - diagnostic imaging Diagnosis Diagnosis, Differential Diagnostic systems Differential diagnosis Humans Imaging Invited Review Lung - diagnostic imaging Medical diagnosis Medicine Medicine & Public Health Nuclear Medicine Opacity Patients Radiology Radiotherapy Retrospective Studies SARS-CoV-2 Signs and symptoms Thorax Viral diseases COVID-19 Differential diagnosis Coronavirus Computed tomography Ground-glass opacity
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Abstract	Thoracic imaging is fundamental in the diagnostic route of Coronavirus disease 2019 (COVID-19) especially in patients admitted to hospitals. In particular, chest computed tomography (CT) has a key role in identifying the typical features of the infection. Ground-glass opacities (GGO) are one of the main CT findings, but their presence is not specific for this viral pneumonia. In fact, GGO is a radiological sign of different pathologies with both acute and subacute/chronic clinical manifestations. In the evaluation of a subject with focal or diffuse GGO, the radiologist has to know the patient’s medical history to obtain a valid diagnostic hypothesis. The authors describe the various CT appearance of GGO, related to the onset of symptoms, focusing also on the ancillary signs that can help radiologist to obtain a correct and prompt diagnosis.
AbstractList	Thoracic imaging is fundamental in the diagnostic route of Coronavirus disease 2019 (COVID-19) especially in patients admitted to hospitals. In particular, chest computed tomography (CT) has a key role in identifying the typical features of the infection. Ground-glass opacities (GGO) are one of the main CT findings, but their presence is not specific for this viral pneumonia. In fact, GGO is a radiological sign of different pathologies with both acute and subacute/chronic clinical manifestations. In the evaluation of a subject with focal or diffuse GGO, the radiologist has to know the patient's medical history to obtain a valid diagnostic hypothesis. The authors describe the various CT appearance of GGO, related to the onset of symptoms, focusing also on the ancillary signs that can help radiologist to obtain a correct and prompt diagnosis. Thoracic imaging is fundamental in the diagnostic route of Coronavirus disease 2019 (COVID-19) especially in patients admitted to hospitals. In particular, chest computed tomography (CT) has a key role in identifying the typical features of the infection. Ground-glass opacities (GGO) are one of the main CT findings, but their presence is not specific for this viral pneumonia. In fact, GGO is a radiological sign of different pathologies with both acute and subacute/chronic clinical manifestations. In the evaluation of a subject with focal or diffuse GGO, the radiologist has to know the patient's medical history to obtain a valid diagnostic hypothesis. The authors describe the various CT appearance of GGO, related to the onset of symptoms, focusing also on the ancillary signs that can help radiologist to obtain a correct and prompt diagnosis.Thoracic imaging is fundamental in the diagnostic route of Coronavirus disease 2019 (COVID-19) especially in patients admitted to hospitals. In particular, chest computed tomography (CT) has a key role in identifying the typical features of the infection. Ground-glass opacities (GGO) are one of the main CT findings, but their presence is not specific for this viral pneumonia. In fact, GGO is a radiological sign of different pathologies with both acute and subacute/chronic clinical manifestations. In the evaluation of a subject with focal or diffuse GGO, the radiologist has to know the patient's medical history to obtain a valid diagnostic hypothesis. The authors describe the various CT appearance of GGO, related to the onset of symptoms, focusing also on the ancillary signs that can help radiologist to obtain a correct and prompt diagnosis.
Author	Zantonelli, Giulia Smorchkova, Olga Cavigli, Edoardo Pradella, Silvia Miele, Vittorio Cozzi, Diletta Moroni, Chiara
Author_xml	– sequence: 1 givenname: Diletta orcidid: 0000-0001-7028-9047 surname: Cozzi fullname: Cozzi, Diletta email: dilettacozzi@gmail.com organization: Department of Emergency Radiology, Careggi University Hospital – sequence: 2 givenname: Edoardo orcidid: 0000-0002-2078-0222 surname: Cavigli fullname: Cavigli, Edoardo organization: Department of Emergency Radiology, Careggi University Hospital – sequence: 3 givenname: Chiara surname: Moroni fullname: Moroni, Chiara organization: Department of Emergency Radiology, Careggi University Hospital – sequence: 4 givenname: Olga surname: Smorchkova fullname: Smorchkova, Olga organization: Department of Emergency Radiology, Careggi University Hospital – sequence: 5 givenname: Giulia surname: Zantonelli fullname: Zantonelli, Giulia organization: Department of Emergency Radiology, Careggi University Hospital – sequence: 6 givenname: Silvia surname: Pradella fullname: Pradella, Silvia organization: Department of Emergency Radiology, Careggi University Hospital, SIRM Foundation – sequence: 7 givenname: Vittorio orcidid: 0000-0002-7848-1567 surname: Miele fullname: Miele, Vittorio organization: Department of Emergency Radiology, Careggi University Hospital
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Keywords	COVID-19 Differential diagnosis Coronavirus Computed tomography Ground-glass opacity
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Snippet	Thoracic imaging is fundamental in the diagnostic route of Coronavirus disease 2019 (COVID-19) especially in patients admitted to hospitals. In particular,...
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SubjectTerms	Computed tomography Coronaviruses COVID-19 COVID-19 - diagnostic imaging Diagnosis Diagnosis, Differential Diagnostic systems Differential diagnosis Humans Imaging Invited Review Lung - diagnostic imaging Medical diagnosis Medicine Medicine & Public Health Nuclear Medicine Opacity Patients Radiology Radiotherapy Retrospective Studies SARS-CoV-2 Signs and symptoms Thorax Viral diseases
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Title	Ground-glass opacity (GGO): a review of the differential diagnosis in the era of COVID-19
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