Comparison of serum metabolomics in women with breast Cancer Prior to Chemotherapy and at 1 year: cardiometabolic implications

• Published in: BMC women's health Vol. 23; no. 1; pp. 221 - 10
• Main Authors: Lyon, Debra E., Yao, Yingwei, Garrett, Timothy, Kelly, Debra Lynch, Cousin, Lakeshia, Archer, Kellie J.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 03.05.2023; BioMed Central; BMC
• Subjects: African American women; Amines; Amino acids; Amino Acids - metabolism; Analysis; Biological samples; Biosynthesis; Black people; Breast cancer; Breast Neoplasms - drug therapy; Cancer; Cancer therapies; Cardiovascular Diseases; Care and treatment; Chemotherapy; Diagnosis; Ethnicity; Fatty acids; Female; Health aspects; Health risks; Hispanic Americans; Human subjects; Humans; inflammation; Laboratories; Liquid chromatography; Lysine; Mass spectrometry; Metabolism; Metabolites; Metabolomics; Morbidity; Mortality; Patient outcomes; Secondary analysis; Social aspects; Survival; Survivor; survivorship; Synthesis; Tandem Mass Spectrometry; Womens health; United States; United States > US; Virginia; survivorship; breast cancer; inflammation; metabolomics

Early-stage breast cancer (BC) is the second most common malignancy in women, worldwide. Early-detection and treatment advances have led to 5-year survival rates of 90% for early-stage breast cancer. However, the long-term morbidity of breast cancer remains high, with a majority of survivors facing...