Systemic inflammatory biomarkers are novel predictors of all-cause and cardiovascular mortality in individuals with osteoarthritis: a prospective cohort study using data from the NHANES

• Published in: BMC public health Vol. 24; no. 1; pp. 1586 - 13
• Main Authors: Zhou, Erye, Wu, Jian, Zhou, Xin, Yin, Yufeng
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.06.2024; BioMed Central; BMC
• Subjects: Adult; Adults; Aged; Analysis; Arthritis; Biological markers; Biomarker; Biomarkers; Biomarkers - blood; Blood cells; Blood platelets; Blood tests; Body mass index; Cardiovascular diseases; Cardiovascular Diseases - mortality; Cartilage; Cause of Death; Cell culture; Educational attainment; Ethnicity; Fatalities; Female; Health aspects; Health hazards; Health insurance; Health risks; Humans; Inflammation; Inflammation - blood; Inflammation - mortality; Lymphocytes; Male; Measurement; Medical prognosis; Middle Aged; Mortality; Mortality risk; Neutrophils; Nutrition Surveys; Osteoarthritis; Osteoarthritis - blood; Osteoarthritis - mortality; Patient outcomes; Performance prediction; Physiological aspects; Population; Prognosis; Prospective Studies; Regression analysis; Regression models; Risk assessment; Statistical analysis; Statistical models; Surveys; Systemic inflammation; Time dependence; United States - epidemiology; United States; United States > US; Biomarker; Osteoarthritis; Mortality; Systemic inflammation

Chronic inflammation may contribute to increased mortality risk in individuals with osteoarthritis (OA), but research on the prognostic value of inflammatory biomarkers is limited. We aimed to evaluate the associations of the systemic immune-inflammation index (SII) and systemic inflammation respons...