Application of next-generation sequencing on diagnosis of bloodstream infection caused by Mycoplasma hominis in a patient with ANCA-associated vasculitis

• Published in: Annals of clinical microbiology and antimicrobials Vol. 22; no. 1; pp. 28 - 7
• Main Authors: Chen, Yili, Chen, Hengxin, Huang, Hao, Zhong, Yinyin, Lin, Xiaoshu, Chen, Peisong, Liao, Kang, Yang, Juhua, Liu, Min, Hong, Mengzhi, Wang, Ruizhi
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 21.04.2023; BioMed Central; BMC
• Subjects: Abscesses; Analysis; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - complications; Antibiotics; Antibodies; Antineutrophil cytoplasmic antibodies; Autoantibodies; Bacteria; Bloodstream infection; Body temperature; Care and treatment; Case Report; Combined treatment; Control; Diagnosis; DNA sequencing; Epistaxis; Genetic testing; High-Throughput Nucleotide Sequencing; Humans; Identification and classification; Infections; Laboratories; Levofloxacin; Male; Meropenem; Mycoplasma; Mycoplasma hominis; Mycoplasma hominis - genetics; Mycoplasma Infections - diagnosis; Neutrophils; Next generation sequencing; Nucleotide sequencing; Pathogens; Patients; Pleural effusion; Polymyxin B; Sepsis; Testing; Vasculitis; China; Mycoplasma hominis; Diagnosis; Bloodstream infection; Next generation sequencing
• ISSN: 1476-0711; 1476-0711
• DOI: 10.1186/s12941-023-00580-4

Mycoplasma hominis is one of the main opportunistic pathogenic mycoplasmas in humans which has a major impact on patients with bloodstream infections. Because it is difficult to detect or isolate, rapid and accurate diagnosis using improved methods is essential and still challenging for patients wit...