Outcome of cataract surgery in children with presumed trematode-induced granulomatous anterior uveitis

• Published in: BMC ophthalmology Vol. 24; no. 1; p. 21
• Main Authors: Abdallah, Mona, Al-Hussaini, Ashraf K, Soliman, Wael, Saleh, Mohamed G A
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 15.01.2024; BioMed Central; BMC
• Subjects: Acuity; Analysis; Animals; Anterior chamber; Cataract; Cataract - complications; Cataracts; Child; Complications; Cornea; Difluprednate; Edema; Endothelial cells; Endothelium; Eye; Eye surgery; Granuloma; Granulomas; Humans; Inflammation; Intraocular lenses; Medical research; Medicine, Experimental; Patient outcomes; Patients; Phacoemulsification - adverse effects; Postoperative; Postoperative Complications - surgery; Retrospective Studies; Statistical analysis; Steroids; Surgery; Treatment Outcome; Trematoda; Trematode; Tropical diseases; Uveitis; Uveitis - complications; Uveitis, Anterior - complications; Uveitis, Anterior - surgery; Vision disorders in children; Visual acuity; Egypt; Cataract; Trematode; Uveitis
• DOI: 10.1186/s12886-023-03273-w
• ISSN: 1471-2415

To examine the 6-month visual outcomes and complications following cataract surgery in patients with persumed trematode induced granulomatous anterior uveitis. Assiut university hospital, Assiut, Egypt. This is a retrospective non comparative case series study. Patients presenting with significant cataract secondary to uveitis caused by trematode induced anterior chamber granuloma were included in this study. Cases with active anterior uveitis, within the last 3 months preceding surgery, and those with a history of trauma, were excluded from this study. Data collected included demographic characteristics, history of the condition including when uveitis started, treatment received and history of other health conditions that may be relevant to uveitis.Complete opthalmologic examination including assessment of best corrected visual acuity (BCVA) and OCT macula, if possible, were done. These was repeated 1 week, 1 month, 3 months and 6 months after surgery. Specular microscopy was performed preoperatively and 3 months after surgery. Patients underwent cataract surgery with posterior chamber intra ocular lens and statistical analysis was performed to compare preoperative and postoperative BCVA and corneal endothelial cell counts. Postoperative complications were recorded. Five eyes of 5 patients were included in the study. All study eyes showed improvement in the post-operative visual acuity. A statistically significant improvement was observed in VA in the sixth postoperative month compared to the baseline measurements (p = 0.004). No statistically significant difference was observed between the preoperative and postoperative endothelial cell counts (p = 0.696). Cystoid macular edema did not occur as a postoperative complication. Visual outcomes of cataract surgery in eyes with persumed trematode induced granulametous anterior uveitis are favorable. No sight threatening complication was observed in our series.