Efficacy of beetroot juice on reducing blood pressure in hypertensive adults with autosomal dominant polycystic kidney disease (BEET-PKD): study protocol for a double-blind, randomised, placebo-controlled trial

• Published in: Current controlled trials in cardiovascular medicine Vol. 24; no. 1; pp. 482 - 12
• Main Authors: Sagar, Priyanka S., Munt, Alexandra, Saravanabavan, Sayanthooran, Vahedi, Farnoosh Asghar, Elhindi, James, Nguyen, Beatrice, Chau, Katrina, Harris, David C., Lee, Vincent, Sud, Kamal, Wong, Nikki, Rangan, Gopala K.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 29.07.2023; BioMed Central; BMC
• Subjects: Antihypertensives; Beet sugar; Beetroot juice; Blood pressure; Cardiovascular disease; Care and treatment; Complications and side effects; Creatinine; Diabetes; Diagnosis; Dietary interventions in hypertension; Dietary supplements; Double-blind studies; Ethics; Health aspects; Hospitals; Hypertension; Kidney diseases; Laboratories; Medical research; Medicine; Metabolites; Nitric oxide; Polycystic kidney disease; Properties; Study Protocol; Australia; Beetroot juice; Dietary interventions in hypertension; Polycystic kidney disease

In autosomal dominant polycystic kidney disease (ADPKD) impaired nitric oxide (NO) synthesis, in part, contributes to early-onset hypertension. Beetroot juice (BRJ) reduces blood pressure (BP) by increasing NO-mediated vasodilation. The aim of this double-blind, randomised, placebo-controlled study...