Testing the effects of the GLP-1 receptor agonist exenatide on cocaine self-administration and subjective responses in humans with cocaine use disorder - Angarita, Gustavo A.; Matuskey, David; Pittman, Brian; Costeines, Jessica L.; Potenza, Marc N.; Jastreboff, Ania M.; Schmidt, Heath D.; Malison, Robert T. (Drug and alcohol dependence, 2021)
Keywords: Addictive behaviors; Adult; Amylin; Cocaine; Cocaine - administration & dosage; Cocaine self-administration; Cocaine use disorder; Cocaine-Related Disorders - blood; Cocaine-Related Disorders - drug therapy; Cross-Over Studies; Double-Blind Method; Drug self-administration; Efficacy; Euphoria; Exenatide; Exenatide - pharmacology; Female; GLP-1; GLP-1 receptor agonists; Glucagon; Glucagon-like peptide 1; Glucagon-Like Peptide 1 - blood; Glucagon-Like Peptide 1 - drug effects; Glucagon-Like Peptide-1 Receptor - agonists; Health services utilization; Help seeking behavior; Hormone levels; Humans; Incretins - pharmacology; Insulin; Insulin - blood; Islet Amyloid Polypeptide - blood; Islet Amyloid Polypeptide - drug effects; Male; Management; Middle Aged; Placebos; Pretreatment; Self Administration; Substance-related disorders; Tempering; Treatment Outcome; GLP-1; Cocaine use disorder; Substance-related disorders; Exenatide; Cocaine self-administration; Addictive behaviors