Radical Cystectomy Compared to Combined Modality Treatment for Muscle-Invasive Bladder Cancer: A Systematic Review and Meta-Analysis

• Published in: International journal of radiation oncology, biology, physics Vol. 97; no. 5; pp. 1002 - 1020
• Main Authors: Vashistha, Vishal, Wang, Hanzhang, Mazzone, Andrew, Liss, Michael A., Svatek, Robert S., Schleicher, Mary, Kaushik, Dharam
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2017
• Subjects: Aged; Aged, 80 and over; BLADDER; Chemoradiotherapy - mortality; Chemoradiotherapy - statistics & numerical data; CHEMOTHERAPY; Combined Modality Therapy; Cystectomy - mortality; Cystectomy - statistics & numerical data; Disease-Free Survival; Female; Hematology, Oncology and Palliative Medicine; Humans; Male; Middle Aged; Neoplasm Invasiveness; NEOPLASMS; Postoperative Complications - mortality; Postoperative Complications - prevention & control; Prevalence; Radiation Injuries - mortality; Radiation Injuries - prevention & control; RADICALS; Radiology; RADIOLOGY AND NUCLEAR MEDICINE; RADIOTHERAPY; Risk Factors; Survival Rate; Treatment Outcome; Urinary Bladder Neoplasms - mortality; Urinary Bladder Neoplasms - therapy

To perform a comprehensive comparison of overall survival (OS), disease-specific survival (DSS), progression-free survival (PFS), and treatment-related complications between radical cystectomy (RC) and combined modality treatment (CMT—radiation therapy, concurrent chemotherapy, and maximal transuret...