High-frequency heart rate variability and cortico-striatal activity in men and women with social phobia

Identifying brain systems that regulate or modulate autonomic nervous system functions may identify pathways through which psychosocial factors can influence health and disease. Reduced high-frequency heart rate variability (HF-HRV) characterizes anxiety disordered patients and is predictive of adve...

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Published inNeuroImage (Orlando, Fla.) Vol. 47; no. 3; pp. 815 - 820
Main Authors Åhs, Fredrik, Sollers, John J., Furmark, Tomas, Fredrikson, Mats, Thayer, Julian F.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.09.2009
Elsevier Limited
Subjects
Adult
Anxiety
autonomic nervous system
Autonomic Nervous System - diagnostic imaging
Autonomic Nervous System - physiopathology
Brain
Brain - blood supply
Brain - diagnostic imaging
Brain - physiopathology
Brain Mapping
Cerebrovascular Circulation - physiology
Electrocardiography
Emotions
Fear & phobias
Female
Gender differences
Heart
Heart rate
Heart Rate - physiology
Heart rate variability
Humans
Male
Medical imaging
MEDICIN
MEDICINE
Mens health
PET
phobic disorders
Phobic Disorders - diagnostic imaging
Phobic Disorders - physiopathology
Positron-Emission Tomography
Regional cerebral blood flow
Sex Characteristics
social phobia
Stress
Studies
Task forces
Womens health
Anxiety
Regional cerebral blood flow
Heart rate variability
Stress
PET
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Abstract Identifying brain systems that regulate or modulate autonomic nervous system functions may identify pathways through which psychosocial factors can influence health and disease. Reduced high-frequency heart rate variability (HF-HRV) characterizes anxiety disordered patients and is predictive of adverse myocardial events. Sex differences in the prevalence of anxiety disorders and cardiac diseases implicate the possibility of sex specific neural regulation of HF-HRV. We investigated the correlation between HF-HRV and regional cerebral blood flow (rCBF) in 28 subjects (15 women) with social phobia undergoing a stressful public speaking task. Regional CBF was measured with [15O] water positron emission tomography. Stress induced rCBF correlated positively with HF-HRV in the right supra genual anterior cingulate cortex Brodmann's area (BA) 32, the right head of the caudate nucleus and bilaterally in the medial prefrontal cortex (BA10), extending into the dorsolateral prefrontal cortex (BA46) in the left hemisphere. Men showed larger positive co-variation in the caudate than women. These findings underscore the importance of the emotional division of the anterior cingulate cortex, the prefrontal cortex and the striatum in cardiovagal activity. The study replicates and extends results from published functional neuroimaging studies on cardioregulatory or modulatory areas in healthy subjects to men and women with social phobia. Moreover, caudate functions, possibly related to dopaminergic neurotransmission, have sexually dimorphic effects on vagal modulation of the heart.
AbstractList Identifying brain systems that regulate or modulate autonomic nervous system functions may identify pathways through which psychosocial factors can influence health and disease. Reduced high-frequency heart rate variability (HF-HRV) characterizes anxiety disordered patients and is predictive of adverse myocardial events. Sex differences in the prevalence of anxiety disorders and cardiac diseases implicate the possibility of sex specific neural regulation of HF-HRV. We investigated the correlation between HF-HRV and regional cerebral blood flow (rCBF) in 28 subjects (15 women) with social phobia undergoing a stressful public speaking task. Regional CBF was measured with [(15)O] water positron emission tomography. Stress induced rCBF correlated positively with HF-HRV in the right supra genual anterior cingulate cortex Brodmann's area (BA) 32, the right head of the caudate nucleus and bilaterally in the medial prefrontal cortex (BA10), extending into the dorsolateral prefrontal cortex (BA46) in the left hemisphere. Men showed larger positive co-variation in the caudate than women. These findings underscore the importance of the emotional division of the anterior cingulate cortex, the prefrontal cortex and the striatum in cardiovagal activity. The study replicates and extends results from published functional neuroimaging studies on cardioregulatory or modulatory areas in healthy subjects to men and women with social phobia. Moreover, caudate functions, possibly related to dopaminergic neurotransmission, have sexually dimorphic effects on vagal modulation of the heart.
Identifying brain systems that regulate or modulate autonomic nervous system functions may identify pathways through which psychosocial factors can influence health and disease. Reduced high-frequency heart rate variability (HF-HRV) characterizes anxiety disordered patients and is predictive of adverse myocardial events. Sex differences in the prevalence of anxiety disorders and cardiac diseases implicate the possibility of sex specific neural regulation of HF-HRV. We investigated the correlation between HF-HRV and regional cerebral blood flow (rCBF) in 28 subjects (15 women) with social phobia undergoing a stressful public speaking task. Regional CBF was measured with [ super(15)O] water positron emission tomography. Stress induced rCBF correlated positively with HF-HRV in the right supra genual anterior cingulate cortex Brodmann's area (BA) 32, the right head of the caudate nucleus and bilaterally in the medial prefrontal cortex (BA10), extending into the dorsolateral prefrontal cortex (BA46) in the left hemisphere. Men showed larger positive co-variation in the caudate than women. These findings underscore the importance of the emotional division of the anterior cingulate cortex, the prefrontal cortex and the striatum in cardiovagal activity. The study replicates and extends results from published functional neuroimaging studies on cardioregulatory or modulatory areas in healthy subjects to men and women with social phobia. Moreover, caudate functions, possibly related to dopaminergic neurotransmission, have sexually dimorphic effects on vagal modulation of the heart.
Identifying brain systems that regulate or modulate autonomic nervous system functions may identify pathways through which psychosocial factors can influence health and disease. Reduced high-frequency heart rate variability (HF-HRV) characterizes anxiety disordered patients and is predictive of adverse myocardial events. Sex differences in the prevalence of anxiety disorders and cardiac diseases implicate the possibility of sex specific neural regulation of HF-HRV. We investigated the correlation between HF-HRV and regional cerebral blood flow (rCBF) in 28 subjects (15 women) with social phobia undergoing a stressful public speaking task. Regional CBF was measured with [(15)O] water positron emission tomography. Stress induced rCBF correlated positively with HF-HRV in the right supra genual anterior cingulate cortex Brodmann's area (BA) 32, the right head of the caudate nucleus and bilaterally in the medial prefrontal cortex (BA10), extending into the dorsolateral prefrontal cortex (BA46) in the left hemisphere. Men showed larger positive co-variation in the caudate than women. These findings underscore the importance of the emotional division of the anterior cingulate cortex, the prefrontal cortex and the striatum in cardiovagal activity. The study replicates and extends results from published functional neuroimaging studies on cardioregulatory or modulatory areas in healthy subjects to men and women with social phobia. Moreover, caudate functions, possibly related to dopaminergic neurotransmission, have sexually dimorphic effects on vagal modulation of the heart.Identifying brain systems that regulate or modulate autonomic nervous system functions may identify pathways through which psychosocial factors can influence health and disease. Reduced high-frequency heart rate variability (HF-HRV) characterizes anxiety disordered patients and is predictive of adverse myocardial events. Sex differences in the prevalence of anxiety disorders and cardiac diseases implicate the possibility of sex specific neural regulation of HF-HRV. We investigated the correlation between HF-HRV and regional cerebral blood flow (rCBF) in 28 subjects (15 women) with social phobia undergoing a stressful public speaking task. Regional CBF was measured with [(15)O] water positron emission tomography. Stress induced rCBF correlated positively with HF-HRV in the right supra genual anterior cingulate cortex Brodmann's area (BA) 32, the right head of the caudate nucleus and bilaterally in the medial prefrontal cortex (BA10), extending into the dorsolateral prefrontal cortex (BA46) in the left hemisphere. Men showed larger positive co-variation in the caudate than women. These findings underscore the importance of the emotional division of the anterior cingulate cortex, the prefrontal cortex and the striatum in cardiovagal activity. The study replicates and extends results from published functional neuroimaging studies on cardioregulatory or modulatory areas in healthy subjects to men and women with social phobia. Moreover, caudate functions, possibly related to dopaminergic neurotransmission, have sexually dimorphic effects on vagal modulation of the heart.
Identifying brain systems that regulate or modulate autonomic nervous system functions may identify pathways through which psychosocial factors can influence health and disease. Reduced high-frequency heart rate variability (HF-HRV) characterizes anxiety disordered patients and is predictive of adverse myocardial events. Sex differences in the prevalence of anxiety disorders and cardiac diseases implicate the possibility of sex specific neural regulation of HF-HRV. We investigated the correlation between HF-HRV and regional cerebral blood flow (rCBF) in 28 subjects (15 women) with social phobia undergoing a stressful public speaking task. Regional CBF was measured with [15O] water positron emission tomography. Stress induced rCBF correlated positively with HF-HRV in the right supra genual anterior cingulate cortex Brodmann's area (BA) 32, the right head of the caudate nucleus and bilaterally in the medial prefrontal cortex (BA10), extending into the dorsolateral prefrontal cortex (BA46) in the left hemisphere. Men showed larger positive co-variation in the caudate than women. These findings underscore the importance of the emotional division of the anterior cingulate cortex, the prefrontal cortex and the striatum in cardiovagal activity. The study replicates and extends results from published functional neuroimaging studies on cardioregulatory or modulatory areas in healthy subjects to men and women with social phobia. Moreover, caudate functions, possibly related to dopaminergic neurotransmission, have sexually dimorphic effects on vagal modulation of the heart.
Author Åhs, Fredrik
Fredrikson, Mats
Sollers, John J.
Furmark, Tomas
Thayer, Julian F.
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  givenname: John J.
  surname: Sollers
  fullname: Sollers, John J.
  organization: Department of Psychology, The Ohio State University, Columbus, Ohio, USA
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  givenname: Tomas
  surname: Furmark
  fullname: Furmark, Tomas
  organization: Department of Psychology, Uppsala University, Box 1225, SE-751 42 Uppsala, Sweden
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  surname: Fredrikson
  fullname: Fredrikson, Mats
  organization: Department of Psychology, Uppsala University, Box 1225, SE-751 42 Uppsala, Sweden
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  givenname: Julian F.
  surname: Thayer
  fullname: Thayer, Julian F.
  organization: Department of Psychology, The Ohio State University, Columbus, Ohio, USA
BackLink https://www.ncbi.nlm.nih.gov/pubmed/19505585$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1038/35072584
10.1016/0002-9149(87)90795-8
10.1016/j.biopsych.2005.03.029
10.1093/cvr/24.10.793
10.1016/j.neubiorev.2008.08.004
10.1016/j.genhosppsych.2007.12.006
10.5694/j.1326-5377.1978.tb131339.x
10.1016/S1364-6613(00)01483-2
10.1016/0006-3223(95)00136-0
10.1016/j.biopsycho.2005.08.009
10.1016/j.neuroimage.2008.04.238
10.1176/appi.ajp.2007.07030504
10.1016/j.neuroimage.2008.07.056
10.1016/j.biopsycho.2005.11.013
10.1016/j.neuroimage.2004.03.005
10.1523/JNEUROSCI.2534-08.2008
10.1016/S1053-8119(03)00169-1
10.1159/000414022
10.1097/PSY.0b013e31816baefa
10.1682/JRRD.2007.06.0082
10.1001/archgenpsychiatry.2008.525
10.1038/sj.npp.1301342
10.1016/j.ijpsycho.2008.07.013
10.1016/j.biopsych.2006.03.059
10.1016/j.neulet.2004.02.070
10.1001/archgenpsychiatry.2007.4
10.1126/science.289.5479.591
10.1016/0022-3999(79)90066-7
10.1016/j.biopsych.2006.01.008
10.1006/nimg.1997.0291
10.1016/j.biopsych.2006.03.042
10.1161/01.CIR.93.5.1043
10.1016/j.amjhyper.2006.03.005
10.1111/1469-8986.2004.00179.x
10.1111/j.1749-6632.2003.tb07096.x
10.1093/brain/awg216
10.1038/mp.2008.65
10.1016/S0006-3223(03)00525-0
10.1002/hbm.460020402
10.1097/01.psy.0000242120.91030.d8
10.1002/1097-0193(200007)10:3<120::AID-HBM30>3.0.CO;2-8
10.1016/j.tics.2005.03.010
10.1016/j.biopsycho.2005.08.010
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Issue 3
Keywords Anxiety
Regional cerebral blood flow
Heart rate variability
Stress
PET
Language English
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References Liebowitz (bib24) 1987; 22
Rottenberg (bib38) 2007; 74
Goldin, Manber, Hakimi, Canli, Gross (bib19) 2009; 66
Lancaster, Woldorff, Parsons, Liotti, Freitas, Rainey (bib22) 2000; 10
Gianaros, Van Der Veen, Jennings (bib18) 2004; 41
Phillips, Ladouceur, Drevets (bib35) 2008; 13
Friedman (bib13) 2007; 74
Thayer, Hansen, Johnsen (bib47) 2008
Maldjian, Laurienti, Kraft, Burdette (bib25) 2003; 19
Friston, Buechel, Fink, Morris, Rolls, Dolan (bib14) 1997; 6
Roy-Byrne (bib39) 2008; 30
Woodward, Kaloupek, Schaer, Martinez, Eliez (bib49) 2008; 45
Friston, Holmes, Worsley, Poline, Frith, Frackowiak (bib51) 1994; 2
(bib43) 1996; 93
Davidson, Putnam, Larson (bib9) 2000; 289
Rauch, Shin, Wright (bib36) 2003; 985
Furmark, Appel, Michelgard, Wahlstedt, Ahs, Zancan, Jacobsson, Flyckt, Grohp, Bergstrom, Pich, Nilsson, Bani, Langstrom, Fredrikson (bib16) 2005; 58
Calder, Lawrence, Young (bib7) 2001; 2
Thayer, Lane (bib45) 2009; 33
First, Gibbon, Spitzer, Williams (bib11) 1998
Neumann, Brown, Ferrell, Flory, Manuck, Hariri (bib31) 2006; 60
Thayer, Lane (bib44) 2007; 74
Talairach, Tournoux (bib42) 1988; 59
Malik, Camm (bib26) 1990; 24
Lane, McRae, Reiman, Chen, Ahern, Thayer (bib23) 2009; 44
Kleiger, Miller, Bigger, Moss (bib21) 1987; 59
Melzig, Weike, Hamm, Thayer (bib28) 2009; 71
Napadow, Dhond, Conti, Makris, Brown, Barbieri (bib30) 2008; 42
Etkin, Wager (bib10) 2007; 164
(bib2) 1994
O'Connor, Gündel, McRae, Lane (bib33) 2007; 32
Matthews, Paulus, Simmons, Nelesen, Dimsdale (bib27) 2004; 22
Bleil, Gianaros, Jennings, Flory, Manuck (bib3) 2008; 70
Furmark, Appel, Henningsson, Ahs, Faria, Linnman, Pissiota, Frans, Bani, Bettica, Pich, Jacobsson, Wahlstedt, Oreland, Langstrom, Eriksson, Fredrikson (bib17) 2008; 28
Sheehan, D.V., Lecrubier, Y., Sheehan, K.H., Amorim, P., Janavs, J., Weiller, E. et al., (1998): Stuttgart: Georg Thieme Verlag.
Bush, Luu, Posner (bib6) 2000; 4
Saul (bib40) 1990; 5
Åhs, Furmark, Michelgard, Langstrom, Appel, Wolf, Kirschbaum, Fredrikson (bib1) 2006; 68
Thayer, Friedman, Borkovec (bib46) 1996; 39
Critchley, Mathias, Josephs, O'Doherty, Zanini, Dewar, Cipolotti, Shallice, Dolan (bib8) 2003; 126
Furmark, Tillfors, Garpenstrand, Marteinsdottir, Langstrom, Oreland, Fredrikson (bib15) 2004; 362
Bonne, Gilboa, Louzoun, Brandes, Yona, Lester, Barkai, Freedman, Chisin, Shalev (bib5) 2003; 54
Paulus, Stein (bib34) 2006; 60
Frasure-Smith, Lesperance (bib12) 2008; 65
Munro, McCaul, Wong, Oswald, Zhou, Brasic, Kuwabara, Kumar, Alexander, Ye, Wand (bib29) 2006; 59
Blumenthal, Thompson, Williams, Kong (bib4) 1979; 23
Ochsner, Gross (bib32) 2005; 9
Wolf, Varigos, Hunt, Sloman (bib48) 1978; 2
Yeh, Yang, Chiu, Yao, Yeh, Wu, Chuang, Chang (bib50) 2006; 19
Munro (10.1016/j.neuroimage.2009.05.091_bib29) 2006; 59
Davidson (10.1016/j.neuroimage.2009.05.091_bib9) 2000; 289
Paulus (10.1016/j.neuroimage.2009.05.091_bib34) 2006; 60
Lane (10.1016/j.neuroimage.2009.05.091_bib23) 2009; 44
Gianaros (10.1016/j.neuroimage.2009.05.091_bib18) 2004; 41
Roy-Byrne (10.1016/j.neuroimage.2009.05.091_bib39) 2008; 30
Bonne (10.1016/j.neuroimage.2009.05.091_bib5) 2003; 54
Furmark (10.1016/j.neuroimage.2009.05.091_bib15) 2004; 362
Saul (10.1016/j.neuroimage.2009.05.091_bib40) 1990; 5
(10.1016/j.neuroimage.2009.05.091_bib2) 1994
Wolf (10.1016/j.neuroimage.2009.05.091_bib48) 1978; 2
Furmark (10.1016/j.neuroimage.2009.05.091_bib16) 2005; 58
Ochsner (10.1016/j.neuroimage.2009.05.091_bib32) 2005; 9
Friston (10.1016/j.neuroimage.2009.05.091_bib51) 1994; 2
Thayer (10.1016/j.neuroimage.2009.05.091_bib44) 2007; 74
Blumenthal (10.1016/j.neuroimage.2009.05.091_bib4) 1979; 23
Kleiger (10.1016/j.neuroimage.2009.05.091_bib21) 1987; 59
Yeh (10.1016/j.neuroimage.2009.05.091_bib50) 2006; 19
Lancaster (10.1016/j.neuroimage.2009.05.091_bib22) 2000; 10
Matthews (10.1016/j.neuroimage.2009.05.091_bib27) 2004; 22
Thayer (10.1016/j.neuroimage.2009.05.091_bib47) 2008
Furmark (10.1016/j.neuroimage.2009.05.091_bib17) 2008; 28
Bleil (10.1016/j.neuroimage.2009.05.091_bib3) 2008; 70
Napadow (10.1016/j.neuroimage.2009.05.091_bib30) 2008; 42
O'Connor (10.1016/j.neuroimage.2009.05.091_bib33) 2007; 32
Friedman (10.1016/j.neuroimage.2009.05.091_bib13) 2007; 74
Calder (10.1016/j.neuroimage.2009.05.091_bib7) 2001; 2
Maldjian (10.1016/j.neuroimage.2009.05.091_bib25) 2003; 19
Goldin (10.1016/j.neuroimage.2009.05.091_bib19) 2009; 66
Thayer (10.1016/j.neuroimage.2009.05.091_bib46) 1996; 39
10.1016/j.neuroimage.2009.05.091_bib41
Friston (10.1016/j.neuroimage.2009.05.091_bib14) 1997; 6
Phillips (10.1016/j.neuroimage.2009.05.091_bib35) 2008; 13
Melzig (10.1016/j.neuroimage.2009.05.091_bib28) 2009; 71
Woodward (10.1016/j.neuroimage.2009.05.091_bib49) 2008; 45
First (10.1016/j.neuroimage.2009.05.091_bib11) 1998
Malik (10.1016/j.neuroimage.2009.05.091_bib26) 1990; 24
Talairach (10.1016/j.neuroimage.2009.05.091_bib42) 1988; 59
Thayer (10.1016/j.neuroimage.2009.05.091_bib45) 2009; 33
Rauch (10.1016/j.neuroimage.2009.05.091_bib36) 2003; 985
Neumann (10.1016/j.neuroimage.2009.05.091_bib31) 2006; 60
Critchley (10.1016/j.neuroimage.2009.05.091_bib8) 2003; 126
Rottenberg (10.1016/j.neuroimage.2009.05.091_bib38) 2007; 74
Liebowitz (10.1016/j.neuroimage.2009.05.091_bib24) 1987; 22
(10.1016/j.neuroimage.2009.05.091_bib43) 1996; 93
Åhs (10.1016/j.neuroimage.2009.05.091_bib1) 2006; 68
Etkin (10.1016/j.neuroimage.2009.05.091_bib10) 2007; 164
Bush (10.1016/j.neuroimage.2009.05.091_bib6) 2000; 4
Frasure-Smith (10.1016/j.neuroimage.2009.05.091_bib12) 2008; 65
References_xml – volume: 41
  start-page: 521
  year: 2004
  end-page: 530
  ident: bib18
  article-title: Regional cerebral blood flow correlates with heart period and high-frequency heart period variability during working-memory tasks: implications for the cortical and subcortical regulation of cardiac autonomic activity
  publication-title: Psychophysiology
– reference: Sheehan, D.V., Lecrubier, Y., Sheehan, K.H., Amorim, P., Janavs, J., Weiller, E. et al., (1998): Stuttgart: Georg Thieme Verlag.
– volume: 30
  start-page: 208
  year: 2008
  end-page: 225
  ident: bib39
  article-title: Anxiety disorders and comorbid medical illness
  publication-title: Gen. Hosp. Psych.
– volume: 39
  start-page: 255
  year: 1996
  end-page: 266
  ident: bib46
  article-title: Autonomic characteristics of generalized anxiety disorder and worry
  publication-title: Biol. Psychiatry
– volume: 22
  start-page: 141
  year: 1987
  end-page: 173
  ident: bib24
  article-title: Social phobia
  publication-title: Mod. Probl. Pharmacopsychiatry
– volume: 74
  start-page: 200
  year: 2007
  end-page: 211
  ident: bib38
  article-title: Cardiac vagal control in depression: a critical analysis
  publication-title: Biol. Psychol.
– volume: 33
  start-page: 81
  year: 2009
  end-page: 88
  ident: bib45
  article-title: Claude Bernard and the heart–brain connection: further elaboration of a model of Neurovisceral Integration
  publication-title: Neurosci. Biobehav. Rev.
– volume: 59
  start-page: 966
  year: 2006
  end-page: 974
  ident: bib29
  article-title: Sex differences in striatal dopamine release in healthy adults
  publication-title: Biol. Psychiatry
– volume: 32
  start-page: 2184
  year: 2007
  end-page: 2189
  ident: bib33
  article-title: Baseline vagal tone predicts BOLD response during elicitation of grief
  publication-title: Neuropsychopharmacology
– volume: 65
  start-page: 62
  year: 2008
  end-page: 71
  ident: bib12
  article-title: Depression and anxiety as predictors of 2-year cardiac events in patients with stable coronary artery disease
  publication-title: Arch. Gen. Psychiatry
– volume: 44
  start-page: 213
  year: 2009
  end-page: 222
  ident: bib23
  article-title: Neural correlates of heart rate variability during emotion
  publication-title: NeuroImage
– year: 1994
  ident: bib2
  article-title: Diagnostic and Statistical Manual of Mental Disorders
– volume: 2
  start-page: 352
  year: 2001
  end-page: 363
  ident: bib7
  article-title: Neuropsychology of fear and loathing
  publication-title: Nat. Rev., Neurosci.
– volume: 19
  start-page: 964
  year: 2006
  end-page: 969
  ident: bib50
  article-title: Correlation between striatal dopamine D2/D3 receptor binding and cardiovascular activity in healthy subjects
  publication-title: Am. J. Hypertens.
– volume: 289
  start-page: 591
  year: 2000
  end-page: 594
  ident: bib9
  article-title: Dysfunction in the neural circuitry of emotion regulation—a possible prelude to violence
  publication-title: Science
– volume: 60
  start-page: 1155
  year: 2006
  end-page: 1162
  ident: bib31
  article-title: Human choline transporter gene variation is associated with corticolimbic reactivity and autonomic–cholinergic function
  publication-title: Biol. Psychiatry
– volume: 68
  start-page: 859
  year: 2006
  end-page: 862
  ident: bib1
  article-title: Hypothalamic blood flow correlates positively with stress-induced cortisol levels in subjects with social anxiety disorder
  publication-title: Psychosom. Med.
– volume: 66
  start-page: 170
  year: 2009
  end-page: 180
  ident: bib19
  article-title: Neural bases of social anxiety disorder: emotional reactivity and cognitive regulation during social and physical threat
  publication-title: Arch. Gen. Psychiatry
– volume: 59
  start-page: 256
  year: 1987
  end-page: 262
  ident: bib21
  article-title: Decreased heart rate variability and its association with increased mortality after acute myocardial infarction
  publication-title: Am. J. Cardiol
– volume: 19
  start-page: 1233
  year: 2003
  end-page: 1239
  ident: bib25
  article-title: An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets
  publication-title: NeuroImage
– volume: 2
  start-page: 52
  year: 1978
  end-page: 53
  ident: bib48
  article-title: Sinus arrhythmia in acute myocardial infarction
  publication-title: Med. J. Aust.
– volume: 70
  start-page: 328
  year: 2008
  end-page: 337
  ident: bib3
  article-title: Trait negative affect: toward an integrated model of understanding psychological risk for impairment in cardiac autonomic function
  publication-title: Psychosom. Med.
– volume: 45
  start-page: 451
  year: 2008
  end-page: 463
  ident: bib49
  article-title: Right anterior cingulate cortical volume covaries with respiratory sinus arrhythmia magnitude in combat veterans
  publication-title: J. Rehabil. Res. Dev.
– volume: 10
  start-page: 120
  year: 2000
  end-page: 131
  ident: bib22
  article-title: Automated Talairach atlas labels for functional brain mapping
  publication-title: Hum. Brain Mapp.
– volume: 6
  start-page: 218
  year: 1997
  end-page: 229
  ident: bib14
  article-title: Psychophysiological and modulatory interactions in neuroimaging
  publication-title: NeuroImage
– volume: 985
  start-page: 389
  year: 2003
  end-page: 410
  ident: bib36
  article-title: Neuroimaging studies of amygdala function in anxiety disorders
  publication-title: Ann. N.Y. Acad. Sci.
– volume: 9
  start-page: 242
  year: 2005
  end-page: 249
  ident: bib32
  article-title: The cognitive control of emotion
  publication-title: Trends Cogn. Sci.
– volume: 22
  start-page: 1151
  year: 2004
  end-page: 1156
  ident: bib27
  article-title: Functional subdivisions within anterior cingulate cortex and their relationship to autonomic nervous system function
  publication-title: NeuroImage
– year: 1998
  ident: bib11
  article-title: SCID-I: Interview Protocol (in Swedish)
– volume: 71
  start-page: 109
  year: 2009
  end-page: 117
  ident: bib28
  article-title: Individual differences in fear-potentiated startle as a function of resting heart rate variability: implications for panic disorder
  publication-title: Int. J. Psychophysiol.
– volume: 28
  start-page: 13066
  year: 2008
  end-page: 13074
  ident: bib17
  article-title: A link between serotonin-related gene polymorphisms, amygdala activity, and placebo-induced relief from social anxiety
  publication-title: J. Neurosci.
– volume: 59
  start-page: 22
  year: 1988
  end-page: 33
  ident: bib42
  article-title: Co-planar stereotaxic atlas of the human brain. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10
  publication-title: J. Clin. Psychiatry
– volume: 5
  start-page: 32
  year: 1990
  end-page: 37
  ident: bib40
  article-title: Beat-to beat variations of heart rate reflect modulation of cardiac autonomic outflow
  publication-title: News Physiol. Sci.
– volume: 126
  start-page: 2139
  year: 2003
  end-page: 2152
  ident: bib8
  article-title: Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence
  publication-title: Brain
– volume: 23
  start-page: 17
  year: 1979
  end-page: 21
  ident: bib4
  article-title: Anxiety-proneness and coronary heart disease
  publication-title: J. Psychosom. Res.
– volume: 42
  start-page: 169
  year: 2008
  end-page: 177
  ident: bib30
  article-title: Brain correlates of autonomic modulation: combining heart rate variability with fMRI
  publication-title: NeuroImage
– volume: 4
  start-page: 215
  year: 2000
  end-page: 222
  ident: bib6
  article-title: Cognitive and emotional influences in anterior cingulate cortex
  publication-title: Trends Cogn. Sci.
– volume: 58
  start-page: 132
  year: 2005
  end-page: 142
  ident: bib16
  article-title: Cerebral blood flow changes after treatment of social phobia with the neurokinin-1 antagonist GR205171, citalopram, or placebo
  publication-title: Biol. Psychiatry
– volume: 164
  start-page: 1476
  year: 2007
  end-page: 1488
  ident: bib10
  article-title: Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia
  publication-title: Am. J. Psychiatry
– volume: 2
  start-page: 189
  year: 1994
  end-page: 210
  ident: bib51
  article-title: Statistical parametric maps in functional imaging: a general linear approach
  publication-title: Hum Brain Mapp
– volume: 54
  start-page: 1077
  year: 2003
  end-page: 1086
  ident: bib5
  article-title: Resting regional cerebral perfusion in recent posttraumatic stress disorder
  publication-title: Biol. Psychiatry
– volume: 74
  start-page: 185
  year: 2007
  end-page: 199
  ident: bib13
  article-title: An autonomic flexibility-neurovisceral integration model of anxiety and cardiac vagal tone
  publication-title: Biol. Psychol.
– volume: 24
  start-page: 793
  year: 1990
  end-page: 803
  ident: bib26
  article-title: Significance of long term components of heart rate variability for the further prognosis after acute myocardial infarction
  publication-title: Cardiovasc. Res.
– start-page: 183
  year: 2008
  end-page: 209
  ident: bib47
  article-title: Non-invasive assessment of autonomic influences on the heart: impedance cardiography and heart rate variability
  publication-title: Handbook of Physiological Research Methods in Health Psychology
– volume: 13
  start-page: 833
  year: 2008
  end-page: 857
  ident: bib35
  article-title: A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder
  publication-title: Mol. Psychiatry
– volume: 60
  start-page: 383
  year: 2006
  end-page: 387
  ident: bib34
  article-title: An insular view on anxiety
  publication-title: Biol. Psychiatry
– volume: 93
  start-page: 1043
  year: 1996
  end-page: 1065
  ident: bib43
  article-title: Heart rate variability: standards of measurement, physiological interpretation and clinical use
  publication-title: Circulation
– volume: 74
  start-page: 224
  year: 2007
  end-page: 242
  ident: bib44
  article-title: The role of vagal function in the risk for cardiovascular disease and mortality
  publication-title: Biol. Psychol.
– volume: 362
  start-page: 189
  year: 2004
  end-page: 192
  ident: bib15
  article-title: Serotonin transporter polymorphism related to amygdala excitability and symptom severity in patients with social phobia
  publication-title: Neurosci. Lett.
– volume: 2
  start-page: 352
  year: 2001
  ident: 10.1016/j.neuroimage.2009.05.091_bib7
  article-title: Neuropsychology of fear and loathing
  publication-title: Nat. Rev., Neurosci.
  doi: 10.1038/35072584
– volume: 59
  start-page: 256
  year: 1987
  ident: 10.1016/j.neuroimage.2009.05.091_bib21
  article-title: Decreased heart rate variability and its association with increased mortality after acute myocardial infarction
  publication-title: Am. J. Cardiol
  doi: 10.1016/0002-9149(87)90795-8
– volume: 58
  start-page: 132
  year: 2005
  ident: 10.1016/j.neuroimage.2009.05.091_bib16
  article-title: Cerebral blood flow changes after treatment of social phobia with the neurokinin-1 antagonist GR205171, citalopram, or placebo
  publication-title: Biol. Psychiatry
  doi: 10.1016/j.biopsych.2005.03.029
– volume: 24
  start-page: 793
  year: 1990
  ident: 10.1016/j.neuroimage.2009.05.091_bib26
  article-title: Significance of long term components of heart rate variability for the further prognosis after acute myocardial infarction
  publication-title: Cardiovasc. Res.
  doi: 10.1093/cvr/24.10.793
– volume: 33
  start-page: 81
  year: 2009
  ident: 10.1016/j.neuroimage.2009.05.091_bib45
  article-title: Claude Bernard and the heart–brain connection: further elaboration of a model of Neurovisceral Integration
  publication-title: Neurosci. Biobehav. Rev.
  doi: 10.1016/j.neubiorev.2008.08.004
– volume: 30
  start-page: 208
  year: 2008
  ident: 10.1016/j.neuroimage.2009.05.091_bib39
  article-title: Anxiety disorders and comorbid medical illness
  publication-title: Gen. Hosp. Psych.
  doi: 10.1016/j.genhosppsych.2007.12.006
– start-page: 183
  year: 2008
  ident: 10.1016/j.neuroimage.2009.05.091_bib47
  article-title: Non-invasive assessment of autonomic influences on the heart: impedance cardiography and heart rate variability
– volume: 2
  start-page: 52
  year: 1978
  ident: 10.1016/j.neuroimage.2009.05.091_bib48
  article-title: Sinus arrhythmia in acute myocardial infarction
  publication-title: Med. J. Aust.
  doi: 10.5694/j.1326-5377.1978.tb131339.x
– volume: 4
  start-page: 215
  year: 2000
  ident: 10.1016/j.neuroimage.2009.05.091_bib6
  article-title: Cognitive and emotional influences in anterior cingulate cortex
  publication-title: Trends Cogn. Sci.
  doi: 10.1016/S1364-6613(00)01483-2
– volume: 39
  start-page: 255
  year: 1996
  ident: 10.1016/j.neuroimage.2009.05.091_bib46
  article-title: Autonomic characteristics of generalized anxiety disorder and worry
  publication-title: Biol. Psychiatry
  doi: 10.1016/0006-3223(95)00136-0
– volume: 74
  start-page: 185
  year: 2007
  ident: 10.1016/j.neuroimage.2009.05.091_bib13
  article-title: An autonomic flexibility-neurovisceral integration model of anxiety and cardiac vagal tone
  publication-title: Biol. Psychol.
  doi: 10.1016/j.biopsycho.2005.08.009
– volume: 42
  start-page: 169
  issue: 1
  year: 2008
  ident: 10.1016/j.neuroimage.2009.05.091_bib30
  article-title: Brain correlates of autonomic modulation: combining heart rate variability with fMRI
  publication-title: NeuroImage
  doi: 10.1016/j.neuroimage.2008.04.238
– volume: 164
  start-page: 1476
  year: 2007
  ident: 10.1016/j.neuroimage.2009.05.091_bib10
  article-title: Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia
  publication-title: Am. J. Psychiatry
  doi: 10.1176/appi.ajp.2007.07030504
– volume: 44
  start-page: 213
  issue: 1
  year: 2009
  ident: 10.1016/j.neuroimage.2009.05.091_bib23
  article-title: Neural correlates of heart rate variability during emotion
  publication-title: NeuroImage
  doi: 10.1016/j.neuroimage.2008.07.056
– volume: 5
  start-page: 32
  year: 1990
  ident: 10.1016/j.neuroimage.2009.05.091_bib40
  article-title: Beat-to beat variations of heart rate reflect modulation of cardiac autonomic outflow
  publication-title: News Physiol. Sci.
– volume: 74
  start-page: 224
  year: 2007
  ident: 10.1016/j.neuroimage.2009.05.091_bib44
  article-title: The role of vagal function in the risk for cardiovascular disease and mortality
  publication-title: Biol. Psychol.
  doi: 10.1016/j.biopsycho.2005.11.013
– volume: 22
  start-page: 1151
  issue: 3
  year: 2004
  ident: 10.1016/j.neuroimage.2009.05.091_bib27
  article-title: Functional subdivisions within anterior cingulate cortex and their relationship to autonomic nervous system function
  publication-title: NeuroImage
  doi: 10.1016/j.neuroimage.2004.03.005
– ident: 10.1016/j.neuroimage.2009.05.091_bib41
– volume: 28
  start-page: 13066
  year: 2008
  ident: 10.1016/j.neuroimage.2009.05.091_bib17
  article-title: A link between serotonin-related gene polymorphisms, amygdala activity, and placebo-induced relief from social anxiety
  publication-title: J. Neurosci.
  doi: 10.1523/JNEUROSCI.2534-08.2008
– volume: 19
  start-page: 1233
  year: 2003
  ident: 10.1016/j.neuroimage.2009.05.091_bib25
  article-title: An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets
  publication-title: NeuroImage
  doi: 10.1016/S1053-8119(03)00169-1
– volume: 22
  start-page: 141
  year: 1987
  ident: 10.1016/j.neuroimage.2009.05.091_bib24
  article-title: Social phobia
  publication-title: Mod. Probl. Pharmacopsychiatry
  doi: 10.1159/000414022
– volume: 70
  start-page: 328
  year: 2008
  ident: 10.1016/j.neuroimage.2009.05.091_bib3
  article-title: Trait negative affect: toward an integrated model of understanding psychological risk for impairment in cardiac autonomic function
  publication-title: Psychosom. Med.
  doi: 10.1097/PSY.0b013e31816baefa
– volume: 45
  start-page: 451
  year: 2008
  ident: 10.1016/j.neuroimage.2009.05.091_bib49
  article-title: Right anterior cingulate cortical volume covaries with respiratory sinus arrhythmia magnitude in combat veterans
  publication-title: J. Rehabil. Res. Dev.
  doi: 10.1682/JRRD.2007.06.0082
– volume: 66
  start-page: 170
  year: 2009
  ident: 10.1016/j.neuroimage.2009.05.091_bib19
  article-title: Neural bases of social anxiety disorder: emotional reactivity and cognitive regulation during social and physical threat
  publication-title: Arch. Gen. Psychiatry
  doi: 10.1001/archgenpsychiatry.2008.525
– volume: 32
  start-page: 2184
  issue: 10
  year: 2007
  ident: 10.1016/j.neuroimage.2009.05.091_bib33
  article-title: Baseline vagal tone predicts BOLD response during elicitation of grief
  publication-title: Neuropsychopharmacology
  doi: 10.1038/sj.npp.1301342
– volume: 71
  start-page: 109
  year: 2009
  ident: 10.1016/j.neuroimage.2009.05.091_bib28
  article-title: Individual differences in fear-potentiated startle as a function of resting heart rate variability: implications for panic disorder
  publication-title: Int. J. Psychophysiol.
  doi: 10.1016/j.ijpsycho.2008.07.013
– volume: 60
  start-page: 1155
  issue: 10
  year: 2006
  ident: 10.1016/j.neuroimage.2009.05.091_bib31
  article-title: Human choline transporter gene variation is associated with corticolimbic reactivity and autonomic–cholinergic function
  publication-title: Biol. Psychiatry
  doi: 10.1016/j.biopsych.2006.03.059
– volume: 362
  start-page: 189
  year: 2004
  ident: 10.1016/j.neuroimage.2009.05.091_bib15
  article-title: Serotonin transporter polymorphism related to amygdala excitability and symptom severity in patients with social phobia
  publication-title: Neurosci. Lett.
  doi: 10.1016/j.neulet.2004.02.070
– volume: 65
  start-page: 62
  year: 2008
  ident: 10.1016/j.neuroimage.2009.05.091_bib12
  article-title: Depression and anxiety as predictors of 2-year cardiac events in patients with stable coronary artery disease
  publication-title: Arch. Gen. Psychiatry
  doi: 10.1001/archgenpsychiatry.2007.4
– volume: 289
  start-page: 591
  year: 2000
  ident: 10.1016/j.neuroimage.2009.05.091_bib9
  article-title: Dysfunction in the neural circuitry of emotion regulation—a possible prelude to violence
  publication-title: Science
  doi: 10.1126/science.289.5479.591
– volume: 23
  start-page: 17
  year: 1979
  ident: 10.1016/j.neuroimage.2009.05.091_bib4
  article-title: Anxiety-proneness and coronary heart disease
  publication-title: J. Psychosom. Res.
  doi: 10.1016/0022-3999(79)90066-7
– year: 1994
  ident: 10.1016/j.neuroimage.2009.05.091_bib2
– volume: 59
  start-page: 966
  issue: 10
  year: 2006
  ident: 10.1016/j.neuroimage.2009.05.091_bib29
  article-title: Sex differences in striatal dopamine release in healthy adults
  publication-title: Biol. Psychiatry
  doi: 10.1016/j.biopsych.2006.01.008
– volume: 59
  start-page: 22
  issue: Suppl. 20
  year: 1988
  ident: 10.1016/j.neuroimage.2009.05.091_bib42
  article-title: Co-planar stereotaxic atlas of the human brain. The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10
  publication-title: J. Clin. Psychiatry
– volume: 6
  start-page: 218
  year: 1997
  ident: 10.1016/j.neuroimage.2009.05.091_bib14
  article-title: Psychophysiological and modulatory interactions in neuroimaging
  publication-title: NeuroImage
  doi: 10.1006/nimg.1997.0291
– volume: 60
  start-page: 383
  year: 2006
  ident: 10.1016/j.neuroimage.2009.05.091_bib34
  article-title: An insular view on anxiety
  publication-title: Biol. Psychiatry
  doi: 10.1016/j.biopsych.2006.03.042
– volume: 93
  start-page: 1043
  year: 1996
  ident: 10.1016/j.neuroimage.2009.05.091_bib43
  article-title: Heart rate variability: standards of measurement, physiological interpretation and clinical use
  publication-title: Circulation
  doi: 10.1161/01.CIR.93.5.1043
– volume: 19
  start-page: 964
  issue: 9
  year: 2006
  ident: 10.1016/j.neuroimage.2009.05.091_bib50
  article-title: Correlation between striatal dopamine D2/D3 receptor binding and cardiovascular activity in healthy subjects
  publication-title: Am. J. Hypertens.
  doi: 10.1016/j.amjhyper.2006.03.005
– volume: 41
  start-page: 521
  issue: 4
  year: 2004
  ident: 10.1016/j.neuroimage.2009.05.091_bib18
  article-title: Regional cerebral blood flow correlates with heart period and high-frequency heart period variability during working-memory tasks: implications for the cortical and subcortical regulation of cardiac autonomic activity
  publication-title: Psychophysiology
  doi: 10.1111/1469-8986.2004.00179.x
– volume: 985
  start-page: 389
  year: 2003
  ident: 10.1016/j.neuroimage.2009.05.091_bib36
  article-title: Neuroimaging studies of amygdala function in anxiety disorders
  publication-title: Ann. N.Y. Acad. Sci.
  doi: 10.1111/j.1749-6632.2003.tb07096.x
– volume: 126
  start-page: 2139
  issue: Pt. 10
  year: 2003
  ident: 10.1016/j.neuroimage.2009.05.091_bib8
  article-title: Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence
  publication-title: Brain
  doi: 10.1093/brain/awg216
– year: 1998
  ident: 10.1016/j.neuroimage.2009.05.091_bib11
– volume: 13
  start-page: 833
  issue: 829
  year: 2008
  ident: 10.1016/j.neuroimage.2009.05.091_bib35
  article-title: A neural model of voluntary and automatic emotion regulation: implications for understanding the pathophysiology and neurodevelopment of bipolar disorder
  publication-title: Mol. Psychiatry
  doi: 10.1038/mp.2008.65
– volume: 54
  start-page: 1077
  year: 2003
  ident: 10.1016/j.neuroimage.2009.05.091_bib5
  article-title: Resting regional cerebral perfusion in recent posttraumatic stress disorder
  publication-title: Biol. Psychiatry
  doi: 10.1016/S0006-3223(03)00525-0
– volume: 2
  start-page: 189
  year: 1994
  ident: 10.1016/j.neuroimage.2009.05.091_bib51
  article-title: Statistical parametric maps in functional imaging: a general linear approach
  publication-title: Hum Brain Mapp
  doi: 10.1002/hbm.460020402
– volume: 68
  start-page: 859
  year: 2006
  ident: 10.1016/j.neuroimage.2009.05.091_bib1
  article-title: Hypothalamic blood flow correlates positively with stress-induced cortisol levels in subjects with social anxiety disorder
  publication-title: Psychosom. Med.
  doi: 10.1097/01.psy.0000242120.91030.d8
– volume: 10
  start-page: 120
  year: 2000
  ident: 10.1016/j.neuroimage.2009.05.091_bib22
  article-title: Automated Talairach atlas labels for functional brain mapping
  publication-title: Hum. Brain Mapp.
  doi: 10.1002/1097-0193(200007)10:3<120::AID-HBM30>3.0.CO;2-8
– volume: 9
  start-page: 242
  year: 2005
  ident: 10.1016/j.neuroimage.2009.05.091_bib32
  article-title: The cognitive control of emotion
  publication-title: Trends Cogn. Sci.
  doi: 10.1016/j.tics.2005.03.010
– volume: 74
  start-page: 200
  year: 2007
  ident: 10.1016/j.neuroimage.2009.05.091_bib38
  article-title: Cardiac vagal control in depression: a critical analysis
  publication-title: Biol. Psychol.
  doi: 10.1016/j.biopsycho.2005.08.010
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SubjectTerms Adult
Anxiety
autonomic nervous system
Autonomic Nervous System - diagnostic imaging
Autonomic Nervous System - physiopathology
Brain
Brain - blood supply
Brain - diagnostic imaging
Brain - physiopathology
Brain Mapping
Cerebrovascular Circulation - physiology
Electrocardiography
Emotions
Fear & phobias
Female
Gender differences
Heart
Heart rate
Heart Rate - physiology
Heart rate variability
Humans
Male
Medical imaging
MEDICIN
MEDICINE
Mens health
PET
phobic disorders
Phobic Disorders - diagnostic imaging
Phobic Disorders - physiopathology
Positron-Emission Tomography
Regional cerebral blood flow
Sex Characteristics
social phobia
Stress
Studies
Task forces
Womens health
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