Supra-additive effect of chronic inflammation and atherogenic dyslipidemia on developing type 2 diabetes among young adults: a prospective cohort study

• Published in: Cardiovascular diabetology Vol. 22; no. 1; p. 181
• Main Authors: Lan, Yulong, Wu, Dan, Cai, Zhiwei, Xu, Yuancheng, Ding, Xiong, Wu, Weiqiang, Lan, Shaocong, Chen, Lan, Guo, Zheng, Balmer, Lois, Li, Xingang, Song, Manshu, Wu, Shouling, Gao, Jingli, Wang, Wei, Chen, Youren
• Format: Journal Article
• Language: English
• Published: England BioMed Central 15.07.2023; BMC
• Subjects: Age composition; Age groups; Aging; Antihypertensives; Atherosclerosis - complications; Atherosclerosis - diagnosis; Atherosclerosis - epidemiology; Blood pressure; Body mass index; C-reactive protein; Cohort analysis; Creatinine; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2 - diagnosis; Diabetes Mellitus, Type 2 - epidemiology; Dyslipidemia; Dyslipidemias - diagnosis; Dyslipidemias - epidemiology; Epidemiology; Glucose; Humans; Hypertension; Inflammation; Inflammation - complications; Inflammation - diagnosis; Inflammation - epidemiology; Insulin; Kidney diseases; Lipids; Metabolic disorders; Prospective Studies; Renal function; Risk Factors; Trends; Type 2 diabetes; Variables; Young Adult; Young adults; China; Type 2 diabetes; Aging; Inflammation; Young adults; Dyslipidemia

Both elevated inflammation and atherogenic dyslipidemia are prominent in young-onset diabetes and are increasingly identified as biologically intertwined processes that contribute to diabetogenesis. We aimed to investigate the age-specific risks of type 2 diabetes (T2D) upon concomitant chronic infl...