A pragmatic, open-label, multi-center, randomized controlled clinical trial on the rotational use of interfaces vs standard of care in patients treated with noninvasive positive pressure ventilation for acute hypercapnic respiratory failure: the ROTAtional-USE of interface STUDY (ROTA-USE STUDY) - Vaschetto, Rosanna; Gregoretti, Cesare; Scotti, Lorenza; De Vita, Nello; Carlucci, Annalisa; Cortegiani, Andrea; Crimi, Claudia; Mattei, Alessio; Scala, Raffaele; Rocca, Eduardo; Longhini, Federico; Cammarota, Gianmaria; et al. (Current controlled trials in cardiovascular medicine, 2023)
Keywords: Adult; Airway management; Care and treatment; Chronic obstructive pulmonary disease; Clinical trials; Complications and side effects; Continuous positive airway pressure; Critical care; Extubation; Hospital costs; Humans; Hypercapnic acute respiratory failure; Intensive care; Interfaces; Internal medicine; Intubation; Medical care; Medicine; Noninvasive ventilation; Noninvasive Ventilation - adverse effects; Noninvasive Ventilation - methods; Ostomy; Patient outcomes; Patients; Positive-Pressure Respiration - adverse effects; Positive-Pressure Respiration - methods; Pressure Ulcer - epidemiology; Pressure Ulcer - prevention & control; Pressure ulcers; Quality management; Research design; Respiratory failure; Respiratory insufficiency; Respiratory Insufficiency - therapy; Rotational use of interfaces; Standard of Care; Study Protocol; Treatment Outcome; Ventilators; Italy; Noninvasive ventilation; Pressure ulcers; Hypercapnic acute respiratory failure; Rotational use of interfaces