Secular trend of Kawasaki disease and its correlation with viral activity in Taiwan: a nationwide population-based study

• Published in: BMC public health Vol. 24; no. 1; pp. 1591 - 8
• Main Authors: Shih, Wei-Liang, Huang, Li-Min, Wu, Mei-Hwan, Chang, Luan-Yin
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.06.2024; BioMed Central; BMC
• Subjects: Acute coronary syndromes; Adolescent; Age groups; Analysis; Aneurysms; Autumn; Cardiovascular diseases; Child; Child, Preschool; Children; Coronary vessels; Correlation; Data mining; Diseases; Etiology; Expenditures; Female; Females; Fever; Heart diseases; Humans; Immunoglobulins; Incidence; Infant; Infant, Newborn; Infants; Kawasaki disease; Male; Males; Medical research; Medicine, Experimental; Mucocutaneous lymph node syndrome; Mucocutaneous Lymph Node Syndrome - epidemiology; National health insurance; Pediatric cardiology; Population studies; Population Surveillance; Population-based studies; Seasonal variations; Seasonality; Seasons; Secular trend; Summer; Surveillance; Taiwan - epidemiology; Trends; Veins & arteries; Viral activity; Viral infections; Young adults; Taiwan; Japan; Kawasaki disease; Secular trend; Viral activity; Seasonality

Kawasaki disease (KD) is the most important acquired heart disease in children. This study investigated annual incidence, seasonality, secular trend and the correlation of KD incidence with viral activity in Taiwan. Through the national health insurance database, we identified KD during 2001-2020. T...