Phenotypic and genotypic characterization of virulence markers and antifungal susceptibility of oral Candida species from diabetic and non-diabetic hemodialysis patients

• Published in: BMC oral health Vol. 23; no. 1; pp. 261 - 11
• Main Authors: Mohammadi, Faezeh, Charkhchian, Maliheh, mirzadeh, Monirsadat
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 04.05.2023; BioMed Central; BMC
• Subjects: Amphotericin B; Analysis; Antifungal agents; Antifungal Agents - pharmacology; Antifungal susceptibility; Antiparasitic agents; Biofilms; Biomass; Candida; Candida - genetics; Candida albicans; Candida glabrata - genetics; Candida species; Care and treatment; Caspofungin; Chronic kidney failure; Diabetes; Diabetes mellitus; Dosage and administration; Drug Resistance, Fungal - genetics; Enzymes; Fluconazole; Gene frequency; Genes; Gentian violet; Hemodialysis; Hemodialysis patients; Humans; HWP1 gene; Itraconazole; Kidney diseases; Laboratories; Microbial Sensitivity Tests; Minimum inhibitory concentration; Oligonucleotides; Oral candidiasis; Peptide Hydrolases - genetics; Phenotype; Phospholipase; Phospholipases; Polymerase chain reaction; Prevention; Risk factors; Species; Susceptibility; Virulence; Virulence - genetics; Virulence factors; Virulence factors; Voriconazole; Yeast; Iran; Antifungal susceptibility; Biofilms; Virulence factors; Candida species; Oral candidiasis

Patients with chronic kidney disease undergoing hemodialysis are often colonized by Candida species with high possibility of fungal infections. The purposes of this study were to determine the prevalence of Candida species, evaluate antifungal susceptibility profile, biofilm formation, proteinase an...