Centenarians, semi and supercentenarians, COVID-19 and Spanish flu: a serological assessment to gain insight into the resilience of older centenarians to COVID-19

• Published in: Immunity & ageing Vol. 21; no. 1; pp. 44 - 10
• Main Authors: Trombetta, Claudia Maria, Accardi, Giulia, Aiello, Anna, Calabrò, Anna, Caruso, Calogero, Ligotti, Mattia Emanuela, Marchi, Serena, Montomoli, Emanuele, Neto, Martin Mayora, Temperton, Nigel, Candore, Giuseppina
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 27.06.2024; BioMed Central; BMC
• Subjects: Aged; Aging; Antibodies; B cells; Centenarians; COVID-19; Epidemics; Epidemiology; Geriatrics; Health aspects; Immune Response; Immunological memory; Inflamm-ageing; Inflammation; Influenza; Neutralising antibodies; Older people; Pandemics; Semi-supercentenarians; Severe acute respiratory syndrome coronavirus 2; Spain; Vaccination; Viral antibodies; Viral infections; Viruses; Spain; Belgium; COVID-19; Centenarians; Inflamm-ageing; Immune Response; Neutralising antibodies; Semi-supercentenarians; Spanish flu; Supercentenarians

Although it is well known that the older people have been the most susceptible to COVID-19, there are conflicting data on the susceptibility of centenarians. Two epidemiological study have shown that older centenarians (> 101 years old at the time of the 2020 pandemic peak) are more resilient tha...