Effect of vaginal lubricants on sperm motility and chromatin integrity: a prospective comparative study

• Published in: Fertility and sterility Vol. 89; no. 2; pp. 375 - 379
• Main Authors: Agarwal, Ashok, Deepinder, Fnu, Cocuzza, Marcello, Short, Robert A., Evenson, Donald P.
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.02.2008; Elsevier Science
• Subjects: Biological and medical sciences; Cells, Cultured; Cellulose - analogs & derivatives; Cellulose - pharmacology; Chromatin - drug effects; Chromatin - metabolism; chromatin integrity; DNA Fragmentation - drug effects; Female; Glycerol - pharmacology; Gynecology. Andrology. Obstetrics; Humans; Internal Medicine; Lipids - pharmacology; Lubricants - pharmacology; Male; Medical sciences; Obstetrics and Gynecology; Phosphates - pharmacology; Poloxamer - pharmacology; Polyethylene Glycols - pharmacology; Propylene Glycols - pharmacology; sperm motility; Sperm Motility - drug effects; Spermatozoa - drug effects; Spermatozoa - metabolism; trying to conceive; Vaginal Creams, Foams, and Jellies - pharmacology; Vaginal lubricants; chromatin integrity; Vaginal lubricants; sperm motility; trying to conceive; Chromatin; Motility; Semen; Gynecology; Vagina; Obstetrics; Lubricant; Prospective; Comparative study; Integrity

To evaluate the effect of vaginal lubricants Pre∼Seed, FemGlide, Astroglide, and Replens on human sperm motility and chromatin integrity. Prospective, comparative, in vitro study. Andrology laboratory at tertiary care hospital. Thirteen normozoospermic donors. Semen samples from 13 subjects were inc...