Comparison of the outcomes after haploidentical and cord blood salvage transplantations for graft failure following allogeneic hematopoietic stem cell transplantation

• Published in: Bone marrow transplantation (Basingstoke) Vol. 55; no. 9; pp. 1784 - 1795
• Main Authors: Harada, Kaito, Fuji, Shigeo, Seo, Sachiko, Kanda, Junya, Ueki, Toshimitsu, Kimura, Fumihiko, Kato, Koji, Uchida, Naoyuki, Ikegame, Kazuhiro, Onizuka, Makoto, Matsuoka, Ken-ichi, Doki, Noriko, Kawakita, Toshiro, Onishi, Yasushi, Yano, Shingo, Fukuda, Takahiro, Takanashi, Minoko, Kanda, Yoshinobu, Atsuta, Yoshiko, Ogata, Masao
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 01.09.2020; Nature Publishing Group
• Subjects: 692/699; 692/700/1750; Antithymocyte globulin; Blood; Cell Biology; Comparative analysis; Cord blood; Engraftment; Fatalities; Fetal Blood; Graft rejection; Graft vs Host Disease; Graft-versus-host reaction; Grafting; Grafts; Hematology; Hematopoietic Stem Cell Transplantation - adverse effects; Hematopoietic stem cells; Humans; Internal Medicine; Medicine; Medicine & Public Health; Mortality; Public Health; Stem cell transplantation; Stem Cells; Transplantation; Transplantation Conditioning; Transplants & implants

Graft failure (GF) is a life-threatening complication after allogeneic stem cell transplantation (SCT). Although salvage SCTs can be performed with haploidentical donor (HID) or cord blood (CB), no study has compared the performances of these two sources. Using nationwide registration data, we compa...