Tidal lung hysteresis to interpret PEEP-induced changes in compliance in ARDS patients

• Published in: Critical care (London, England) Vol. 27; no. 1; p. 233
• Main Authors: Mojoli, Francesco, Pozzi, Marco, Arisi, Eric, Mongodi, Silvia, Orlando, Anita, Maggio, Giuseppe, Capra Marzani, Federico, Brochard, Laurent
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.06.2023; BioMed Central; BMC
• Subjects: Body Fluids; Continuous positive airway pressure; COVID-19; Critical care; Decremental PEEP trial; Health aspects; Humans; Hysteresis; Lung; Lung hysteresis; Lung recruitability; Mechanics; Methods; Patient compliance; Patient outcomes; Patients; PEEP setting; Pressure–volume curves; Respiratory Distress Syndrome - therapy; Respiratory system; Tidal recruitment; Variance analysis; Ventilators; United Kingdom; Lung hysteresis; Pressure–volume curves; Lung recruitability; Tidal recruitment; Decremental PEEP trial; PEEP setting

In ARDS, the PEEP level associated with the best respiratory system compliance is often selected; however, intra-tidal recruitment can increase compliance, falsely suggesting improvement in baseline mechanics. Tidal lung hysteresis increases with intra-tidal recruitment and can help interpreting cha...