Inflammation and Alzheimer's disease: Possible role of periodontal diseases

• Published in: Alzheimer's & dementia Vol. 4; no. 4; pp. 242 - 250
• Main Authors: Kamer, Angela R, Craig, Ronald G, Dasanayake, Ananda P, Brys, Miroslaw, Glodzik-Sobanska, Lidia, de Leon, Mony J
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.07.2008
• Subjects: Alzheimer Disease - etiology; Alzheimer Disease - pathology; Alzheimer's disease; C-reactive protein; Central nervous system; Disease Progression; Elevation; Humans; Infection; Inflammation; Inflammation - complications; Inflammation - microbiology; Inflammation - pathology; Neurology; Pathogenesis model; Periodontal Diseases - complications; Periodontal Diseases - pathology; Periodontitis; Risk Factors; Inflammation; Periodontitis; Pathogenesis model; Alzheimer's disease

Abstract The molecular and cellular mechanisms responsible for the etiology and pathogenesis of Alzheimer's disease (AD) have not been defined; however, inflammation within the brain is thought to play a pivotal role. Studies suggest that peripheral infection/inflammation might affect the infla...