Glucose metabolic disorder in Klinefelter syndrome: a retrospective analysis in a single Chinese hospital and literature review

• Published in: BMC endocrine disorders Vol. 21; no. 1; pp. 239 - 10
• Main Authors: Liu, Shixuan, Yuan, Tao, Song, Shuoning, Chen, Shi, Wang, Linjie, Fu, Yong, Dong, Yingyue, Tang, Yan, Zhao, Weigang
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 01.12.2021; BioMed Central; BMC
• Subjects: Adolescent; Analysis; Beta cells; Blood glucose; Blood pressure; Blood sugar; Body mass index; Child; China - epidemiology; Diabetes; Diabetes mellitus; Diabetes Mellitus - epidemiology; Dyslipidemia; Dyslipidemias - epidemiology; Electronic medical records; Glucose; Glucose metabolism; Glucose Metabolism Disorders - epidemiology; Glucose tolerance; Glucose tolerance tests; Health aspects; Homeostasis; Hospitals; Humans; Hyperglycemia; Hyperglycemia - epidemiology; Hypertension; Hypertension - epidemiology; Hypoglycemia; Hypoglycemic therapy; Insulin; Insulin Resistance; Insulin secretion; Insulin-Secreting Cells - physiology; Klinefelter syndrome; Klinefelter Syndrome - epidemiology; Klinefelter Syndrome - physiopathology; Klinefelter's syndrome; Laboratories; Literature reviews; Male; Medical records; Medical research; Medicine, Experimental; Metabolic disorders; Metabolic syndrome; Pancreatic beta cells; Patients; Population; Prediabetic state; Prediabetic State - epidemiology; Retrospective Studies; Secretion; Values; Young Adult; China; Klinefelter syndrome; Insulin resistance; Hyperglycemia; Hypoglycemic therapy; Diabetes mellitus

We aimed to investigate the clinical characteristics and islet β-cell function in patients with Klinefelter syndrome (KS) and hyperglycemia. This is a retrospective study. In total, 22 patients diagnosed with KS were identified from the electronic medical record system, including 9 patients with hyp...