G6PD deficiency in malaria endemic areas of Nepal

• Published in: Malaria journal Vol. 19; no. 1; p. 287
• Main Authors: Marasini, Baburam, Lal, Bibek Kumar, Thapa, Suman, Awasthi, Kiran Raj, Bajracharya, Bijay, Khanal, Pratik, Neupane, Sanjeev, Jha, Shambhu Nath, Acharya, Sanjaya, Iama, Smriti, Koirala, Madan, Koirala, Dinesh, Bhandari, Suresh, Mahato, Ram Kumar, Chaudhary, Arun, Ghimire, Pramin, Magar, Rahachan Gharti, Bhattarai, Rajan Kumar, Gornsawun, Gornpan, Penpitchaporn, Pimsupah, Bancone, Germana, Acharya, Bhim Prasad
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 12.08.2020; BioMed Central; BMC
• Subjects: 8-Aminoquinolines; Adolescent; Adult; Age; Aged; Aged, 80 and over; Blood; Care and treatment; Child; Control; Cross-Sectional Studies; Ethnicity; Female; Females; G6PD deficiency; Genotype & phenotype; Genotyping; Geographical distribution; Glucose-6-phosphate dehydrogenase deficiency; Glucosephosphate dehydrogenase; Glucosephosphate Dehydrogenase Deficiency - epidemiology; Glucosephosphate Dehydrogenase Deficiency - genetics; Haemolysis; Health risks; Hemolysis; Households; Human diseases; Humans; Laboratories; Malaria; Malaria, Vivax - parasitology; Male; Males; Middle Aged; Minority & ethnic groups; Mutation; Nepal; Nepal - epidemiology; Phosphates; Plasmodium vivax; Plasmodium vivax - physiology; Population; Population studies; Prevalence; Primaquine; Regions; Risk factors; Sociodemographics; Statistics; Studies; Surveying; Tropical diseases; Vector-borne diseases; Young Adult; Nepal; Asia; Plasmodium vivax; Malaria; Primaquine; G6PD deficiency; Nepal; 8-Aminoquinolines

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is currently a threat to malaria elimination due to risk of primaquine-induced haemolysis in G6PD deficient individuals. The World Health Organization (WHO) recommends G6PD screening before providing primaquine as a radical treatment against vivax...