Berberine ameliorates depression-like behaviors in mice via inhibiting NLRP3 inflammasome-mediated neuroinflammation and preventing neuroplasticity disruption - Qin, Zongshi; Shi, Dong-Dong; Li, Wenqi; Cheng, Dan; Zhang, Ying-Dan; Zhang, Sen; Tsoi, Bun; Zhao, Jia; Wang, Zhen; Zhang, Zhang-Jin (Journal of neuroinflammation, 2023)
Keywords: Analysis; Animals; Antidepressants; Behavior; Berberine; Care and treatment; Corticosterone; Cytokines; Dendritic spines; Depression; Depression, Mental; Diagnosis; Dosage and administration; Drinking water; Hippocampal plasticity; Hippocampus; Hypotheses; Immune system; Immunofluorescence; Inflammasomes; Inflammation; Male; Mental depression; Mice; Mice, Inbred C57BL; Neurogenesis; Neuroinflammation; Neuroinflammatory Diseases; Neuronal Plasticity; Neuroplasticity; NLR Family, Pyrin Domain-Containing 3 Protein; NLRP3 inflammasome; Oral administration; Pathophysiology; Preferences; Prefrontal cortex; Reverse transcription; Software; Stress response; Sucrose; Synaptic plasticity; Western blotting; Germany; United States--US; Berberine; Depression; Neuroinflammation; NLRP3 inflammasome; Synaptic plasticity