Role of postoperative chemoradiotherapy in head and neck cancer without positive margins or extracapsular extension: a propensity score-matching analysis

• Published in: Radiation oncology (London, England) Vol. 17; no. 1; pp. 180 - 10
• Main Authors: Liu, Zhi-Qiao, OuYang, Pu-Yun, Zhang, Bao-Yu, Chen, En-Ni, Xiao, Su-Ming, Yang, Shan-Shan, Yang, Zhong-Yuan, Xie, Fang-Yun
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.11.2022; BioMed Central; BMC
• Subjects: Analysis; Cancer; Cancer therapies; Care and treatment; Chemoradiotherapy; Chemoradiotherapy - methods; Chemotherapy; Diagnosis; Extranodal Extension; Head & neck cancer; Head and neck cancer; Head and neck carcinoma; Head and Neck Neoplasms - pathology; Head and Neck Neoplasms - therapy; Humans; Immunotherapy; Intermediate-risk features; Larynx; Lymphatic system; Magnetic resonance imaging; Matching; Metastases; Metastasis; Neoplasm Recurrence, Local - pathology; Neoplasm Staging; Patient outcomes; Postoperative chemoradiotherapy; Postoperative radiotherapy; Prevention; Propensity Score; Propensity scores; Radiation therapy; Radiotherapy; Retrospective Studies; Risk analysis; Risk factors; Squamous cell carcinoma; Squamous Cell Carcinoma of Head and Neck - pathology; Squamous Cell Carcinoma of Head and Neck - therapy; Surgery; Survival; Survival analysis; Tomography; Ultrasonic imaging; China; United States > US; Postoperative radiotherapy; Head and neck cancer; Postoperative chemoradiotherapy; Survival; Intermediate-risk features

The aim of this work was to determine whether patients with intermediate-risk head and neck squamous cell carcinoma (HNSCC) can benefit from postoperative chemoradiotherapy (POCRT). Patients without extracapsular extension (ECE) or positive margins (PMs) who received POCRT or postoperative radiother...