Circulating noncoding RNAs as early predictive biomarkers in preeclampsia: a diagnostic meta-analysis

• Published in: Reproductive biology and endocrinology Vol. 19; no. 1; pp. 177 - 10
• Main Authors: Su, Sha, Yang, Fang, Zhong, Linlin, Pang, Lihong
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 01.12.2021; BioMed Central; BMC
• Subjects: Accuracy; Analysis; Bias; Biological markers; Biomarkers; Biomarkers - blood; Cell-Free Nucleic Acids - blood; Communications equipment; Diagnostic meta-analysis; Disease; Female; Humans; Hypertension; Medical diagnosis; Meta-analysis; MicroRNA; MicroRNAs; miRNA; ncRNAs; Non-coding RNA; Peripheral blood mononuclear cells; Pre-eclampsia; Pre-Eclampsia - blood; Pre-Eclampsia - diagnosis; Preeclampsia; Pregnancy; Regression analysis; RNA, Long Noncoding - blood; Sample size; Sensitivity and Specificity; Statistical analysis; Biomarkers; Diagnostic meta-analysis; ncRNAs; Preeclampsia

We designed a meta-analysis to evaluate the clinical significance and efficacy of circulating noncoding RNAs (ncRNAs) in the early prediction of preeclampsia. PubMed, Embase and the Cochrane Library were used to search for literature. The combined prediction performance was evaluated by calculating...