Predictive value of a reduction in the level of high-density lipoprotein-cholesterol in patients with non-small-cell lung cancer undergoing radical resection and adjuvant chemotherapy: a retrospective observational study

• Published in: Lipids in health and disease Vol. 20; no. 1; pp. 109 - 14
• Main Authors: Luo, Fan, Zeng, Kang-mei, Cao, Jia-xin, Zhou, Ting, Lin, Su-xia, Ma, Wen-juan, Yang, Yun-peng, Zhang, Zhong-han, Lu, Fei-teng, Huang, Yan, Zhao, Hong-yun, Zhang, Li
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 20.09.2021; BioMed Central; BMC
• Subjects: Adjuvant chemotherapy; Adjuvant treatment; Adult; Aged; Apolipoprotein A-I - blood; Apolipoprotein B-100 - blood; Apolipoproteins; Cancer; Cancer therapies; Carcinoma, Non-Small-Cell Lung - blood; Carcinoma, Non-Small-Cell Lung - diagnosis; Carcinoma, Non-Small-Cell Lung - mortality; Carcinoma, Non-Small-Cell Lung - surgery; Care and treatment; Cell survival; Chemotherapy; Chemotherapy, Adjuvant; Cholesterol; Cholesterol, HDL; Cholesterol, HDL - blood; Cholesterol, LDL - blood; Diabetes; Disease; Disease-Free Survival; Drugs; Fasting; Female; Health aspects; Hepatic lobectomy; High density lipoprotein; High-density lipoprotein-cholesterol; Histology; Humans; Hypertension; Lipids; Lipoproteins; Low density lipoprotein; Lung cancer; Lung cancer, Non-small cell; Lung Neoplasms - blood; Lung Neoplasms - diagnosis; Lung Neoplasms - mortality; Lung Neoplasms - surgery; Male; Measurement; Medical prognosis; Medical screening; Metabolic syndrome; Middle Aged; Neoplasm Staging - methods; Non-small cell lung carcinoma; Non-small-cell lung cancer; Observational studies; Patient outcomes; Patients; Pneumonectomy; Prognosis; Retrospective Studies; Small cell lung carcinoma; Surgery; Triglycerides - blood; Tumors; China; United States > US; Non-small-cell lung cancer; Adjuvant chemotherapy; Prognosis; High-density lipoprotein-cholesterol; Disease-free survival

Cancer patients often exhibit chemotherapy-associated changes in serum lipid profiles, however, their prognostic value before and after adjuvant chemotherapy on survival among non-small-cell lung cancer (NSCLC) patients is unknown. NSCLC patients undergoing radical resection and subsequent adjuvant...