Serum lipids are associated with nonalcoholic fatty liver disease: a pilot case-control study in Mexico

• Published in: Lipids in health and disease Vol. 20; no. 1; pp. 136 - 17
• Main Authors: Flores, Yvonne N., Amoon, Aryana T., Su, Baolong, Velazquez-Cruz, Rafael, Ramírez-Palacios, Paula, Salmerón, Jorge, Rivera-Paredez, Berenice, Sinsheimer, Janet S., Lusis, Aldons J., Huertas-Vazquez, Adriana, Saab, Sammy, Glenn, Beth A., May, Folasade P., Williams, Kevin J., Bastani, Roshan, Bensinger, Steven J.
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 10.10.2021; BioMed Central; BMC
• Subjects: Abuse; Adult; Aged; Alanine; Alanine transaminase; Alcohol abuse; Aspartate aminotransferase; Biomarkers; Biomarkers - blood; Blood lipids; Blood pressure; Body mass index; Case-Control Studies; Cholesterol; Cholesterol - blood; Chronic illnesses; Cirrhosis; Cohort Studies; Complications and side effects; Cross-sectional studies; Development and progression; Diabetes; Diabetes mellitus; Diagnosis; Drug abuse; Esters; Fatty acids; Fatty liver; Female; Genotypes; Glucose; Health aspects; Health care; Hepatitis; High density lipoprotein; Hispanic Americans; Humans; Laboratories; Lipid composition; Lipid metabolism; Lipidomics; Lipids; Liver cirrhosis; Liver diseases; Lysophosphatidylcholines - blood; Male; Measurement; Metabolic syndrome; Mexico; Middle Aged; NAFLD; Non-alcoholic Fatty Liver Disease - blood; Nonalcoholic fatty liver disease; Physiological aspects; Risk factors; ROC Curve; Serum lipids; Sphingomyelins - blood; Triacylglycerol desaturation; Triglycerides; Triglycerides - blood; Ultrasonic imaging; Ultrasound; Mexico; United States > US; Triacylglycerol desaturation; Mexican; NAFLD; Biomarkers; Lipidomics; Nonalcoholic fatty liver disease; Triglycerides; Cross-sectional study; Latinos

Nonalcoholic fatty liver disease (NAFLD) is a leading cause of chronic liver disease and cirrhosis. NAFLD is mediated by changes in lipid metabolism and known risk factors include obesity, metabolic syndrome, and diabetes. The aim of this study was to better understand differences in the lipid compo...