CRISPR/Cas9 from bench to bedside: what clinicians need to know before application?

• Published in: Military medical research Vol. 7; no. 1; pp. 61 - 3
• Main Authors: Li, Zi-Qing, Li, Chao-Hong
• Format: Journal Article
• Language: English
• Published: England BioMed Central 08.12.2020; BMC
• Subjects: CRISPR; CRISPR-Cas Systems; CRISPR/Cas9; Deoxyribonucleic acid; Design; DNA; Embryos; Ethical concerns; Ethics; Gene therapy; Genetic engineering; Genome editing; Genomes; Hospitals; Humans; Joint surgery; Laboratories; Letter to the Editor; Nobel prize; Nobel prizes; Off-target effect; Point-of-Care Systems - trends; China; Nobel prize; Off-target effect; Genome editing; CRISPR/Cas9; Ethical concerns

In October 2020, Dr. Emmanuelle Charpentier and Dr. Jennifer Doudna won the Nobel Prize in Chemistry for their pioneering work in precise genome editing using the CRISPR technology. Although CRISPR technology has developed rapidly in the last decade, there are still many uncertainties before eventua...