Leptin Receptor (LEPR) promotes proliferation, migration, and invasion and inhibits apoptosis in hepatocellular carcinoma by regulating ANXA7

• Published in: Cancer cell international Vol. 21; no. 1; p. 4
• Main Authors: Huang, He, Zhang, Jun, Ling, Fei, Huang, Yuhong, Yang, Min, Zhang, Yao, Wei, Yuanyi, Zhang, Qingqing, Wang, Honghai, Song, Lin, Wu, Ying, Yang, Jiayu, Tang, Jianwu
• Format: Journal Article
• Language: English
• Published: England BioMed Central 04.01.2021; BMC
• Subjects: ANXA7; Apoptosis; Bioinformatics; Cell adhesion & migration; Cell growth; cell migration; Cell proliferation; Enzymes; Gastric cancer; Hepatocellular carcinoma; Immunofluorescence; Immunohistochemistry; interacting proteins; Janus kinase 2; Kinases; Laboratories; LEPR; Liver cancer; Membranes; Metastases; Metastasis; Microscopy; Plasmids; Primary Research; Proteins; Software; Stat3 protein; Therapeutic targets; Tumors; Western blotting; United States > US; China; Japan; interacting proteins; cell proliferation; LEPR; cell migration; ANXA7; apoptosis; hepatocellular carcinoma

Leptin Receptor (LEPR) has been suggested to have several roles in cancer metastasis. However, the role of LEPR and its underlying mechanisms in lymphatic metastasis of hepatocarcinoma have not yet been studied. We performed bioinformatics analysis, qRT-PCR, western blotting, immunohistochemistry, i...