Risk factors for long-term survival in patients with ypN+ M0 rectal cancer after radical anterior resection

• Published in: BMC gastroenterology Vol. 22; no. 1; pp. 141 - 11
• Main Authors: Zeman, Marcin, Skałba, Władysław, Szymański, Piotr, Hadasik, Grzegorz, Żaworonkow, Dmytro, Walczak, Dominik A., Czarniecka, Agnieszka
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 26.03.2022; BioMed Central; BMC
• Subjects: ACE inhibitors; Adjuvant treatment; Angiotensin; Angiotensin-converting enzyme inhibitors; Antibiotics; Cancer; Cancer therapies; Care and treatment; Chemotherapy; Classification; Clinical outcomes; Colorectal cancer; Complications; Diagnosis; Disease-Free Survival; Dosage and administration; Gastroenterology; Humans; Lymph node metastasis; Lymph node yield; Lymph nodes; Lymphatic metastasis; Lymphatic system; Metastases; Metastasis; Negative lymph node count; Neoadjuvant Therapy; Ostomy; Patients; Peptidyl-dipeptidase A; Postoperative; Prevention; Rectal cancer; Rectal Neoplasms - pathology; Rectal Neoplasms - surgery; Rectum; Renin-angiotensin system; Retrospective Studies; Risk Factors; Surgery; Survival; Poland; Angiotensin-converting enzyme inhibitors; Lymph node metastasis; Rectal cancer; Renin-angiotensin system; Lymph node yield; Negative lymph node count
• ISSN: 1471-230X; 1471-230X
• DOI: 10.1186/s12876-022-02226-9

Regional lymph node metastases are the main adverse prognostic factor in patients with rectal cancer without distant metastases. There are discrepancies, however, regarding additional risk factors in the group of ypN + M0 patients. The purpose of the study was to assess clinical and pathological fac...