Immune landscape and prognostic immune-related genes in KRAS-mutant colorectal cancer patients - Liu, Jungang; Huang, Xiaoliang; Liu, Haizhou; Wei, Chunyin; Ru, Haiming; Qin, Haiquan; Lai, Hao; Meng, Yongsheng; Wu, Guo; Xie, Weishun; Mo, Xianwei; Johnson, Caroline H.; et al. (Journal of translational medicine, 2021)
Keywords: Antigens, Neoplasm; C-reactive protein; Cancer therapies; CD4 antigen; Chemotherapy; Colonic Neoplasms - genetics; Colorectal cancer; Colorectal carcinoma; Colorectal Neoplasms - genetics; Datasets; Development and progression; DNA methylation; Gene expression; Genes, ras; Genetic aspects; Genomes; Growth factors; Health aspects; Hospitals; Human subjects; Humans; Immune system; Immunoglobulin M; Immunological memory; Immunology; Immunoregulation; Immunosuppression; Immunotherapy; Inflammation; K-Ras protein; Kinases; KRAS mutation; Lymphocytes T; Macrophages; Medical prognosis; Memory cells; Metastases; Metastasis; Microenvironments; Mutants; Mutation; Mutation - genetics; NF-κB protein; Prognosis; Proteins; Proto-Oncogene Proteins p21(ras) - genetics; Proto-oncogenes; Radiation therapy; Relaxin; Ribonucleic acid; RNA; Serum levels; Signal transduction; Survival analysis; T cell receptors; Tumor Microenvironment; Tumor-infiltrating immune cells; Tumor-infiltrating lymphocytes; Tumors; China; KRAS mutation; Tumor-infiltrating immune cells; Immunosuppression; Colorectal cancer