Clinical characteristics and outcome of IgG4-related disease with hypocomplementemia: a prospective cohort study

• Published in: Arthritis research & therapy Vol. 23; no. 1; pp. 102 - 10
• Main Authors: Peng, Linyi, Lu, Hui, Zhou, Jiaxin, Zhang, Panpan, Li, Jieqiong, Liu, Zheng, Wu, Di, Zhang, Shangzhu, Yang, Yunjiao, Bai, Wei, Wang, Li, Fei, Yunyun, Zhang, Wen, Zhao, Yan, Zeng, Xiaofeng, Zhang, Fengchun
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 07.04.2021; BioMed Central; BMC
• Subjects: Adult; Age; Aged; Arthritis; Autoimmune diseases; Care and treatment; Clinical outcomes; Cohort analysis; Cohort Studies; Complement; Complement deficiency (Immunology); Diagnosis; Health aspects; Humans; Hypocomplementemia; IgG4-related disease; Immune System Diseases; Immunoglobulin G; Immunoglobulin G4; Immunoglobulin G4-Related Disease - drug therapy; Inflammatory diseases; Kidneys; Male; Medical prognosis; Middle Aged; Patient outcomes; Prospective Studies; Proteins; Relapse; Rheumatology; Treatment Outcome; China; United States > US; Hypocomplementemia; Relapse; Complement; Immunoglobulin G4; IgG4-related disease

Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized systemic, immune-mediated, and fibro-inflammatory disease. Hypocomplementemia was found in part of IgG4-RD patients especially in the setting of active disease. This study aimed to clarify the clinical features, treatment efficacy, an...