A signature of saliva-derived exosomal small RNAs as predicting biomarker for esophageal carcinoma: a multicenter prospective study - Li, Kai; Lin, Yusheng; Luo, Yichen; Xiong, Xiao; Wang, Lu; Durante, Kameron; Li, Junkuo; Zhou, Fuyou; Guo, Yi; Chen, Shaobin; Chen, Yuping; Zhang, Dianzheng; et al. (Molecular cancer, 2022)
Keywords: Biomarkers; Biomarkers, Tumor; Biopsy; Cancer therapies; Combined Modality Therapy; Development and progression; Diagnosis; Disease Management; Endoscopy; Esophageal cancer; Esophageal carcinoma; Esophageal Neoplasms - diagnosis; Esophageal Neoplasms - etiology; Esophageal Neoplasms - metabolism; Esophageal Neoplasms - therapy; Esophagus; Exosomes; Exosomes - metabolism; Female; Gene Expression Profiling; Hospitals; Humans; Hypoxia; Liquid-biopsy signature; Male; Metastasis; Neoplasm Grading; Neoplasm Staging; Nuclease; Pre-operative biomarker of adjuvant therapy; Prognosis; Prospective Studies; RNA sequencing; RNA, Small Untranslated - genetics; RNA, Small Untranslated - metabolism; Saliva; Saliva - metabolism; Sample size; Sensitivity and Specificity; Sequencing of salivary extracellular vesicles; Squamous cell carcinoma; Transfer RNA; Transfer RNA-derived small RNA; tRNA; tRNA-derived fragments; China; Esophageal carcinoma; Liquid-biopsy signature; Transfer RNA-derived small RNA; Pre-operative biomarker of adjuvant therapy; Sequencing of salivary extracellular vesicles; tRNA-derived fragments