Sequential use of midazolam and dexmedetomidine for long-term sedation may reduce weaning time in selected critically ill, mechanically ventilated patients: a randomized controlled study - Zhou, Yongfang; Yang, Jie; Wang, Bo; Wang, Peng; Wang, Zhen; Yang, Yunqin; Liang, Guopeng; jing, Xiaorong; Jin, Xiaodong; Zhang, Zhongwei; Deng, Yiyun; Hu, Chenggong; et al. (Critical care (London, England), 2022)
Keywords: Adult; Anesthesia; Artificial respiration; Cardiac arrhythmia; Care and treatment; Critical care; Critical Illness - therapy; Critically ill; Delirium; Dexmedetomidine; Dexmedetomidine - adverse effects; Dosage and administration; Drug therapy; Drug therapy, Combination; Enrollments; Extubation; Fentanyl; Humans; Hypnotics and Sedatives - pharmacology; Hypnotics and Sedatives - therapeutic use; Hypotension; Mechanical ventilation; Methods; Midazolam; Midazolam - adverse effects; Patients; Propofol; Propofol - adverse effects; Respiration, Artificial; Sequential sedation; Ventilator weaning; Ventilators; Weaning; China; Midazolam; Propofol; Critically ill; Mechanical ventilation; Sequential sedation; Dexmedetomidine