Activation and Repolarization of the Normal Human Heart under Complete Physiological Conditions

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 103; no. 16; pp. 6309 - 6314
• Main Authors: Ramanathan, Charulatha, Jia, Ping, Ghanem, Raja, Ryu, Kyungmoo, Rudy, Yoram
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences 18.04.2006
• Subjects: Adult; Adults; Atrial Function - physiology; Biological Sciences; Canines; Computerized axial tomography; Electrocardiography; Electrocardiography - methods; Epicardium; Female; Heart; Heart - physiology; Humans; Imaging; Male; Mathematical minima; Middle Aged; Pericardium - physiology; Physiology; Ventricular Function - physiology; Wave reflection

Knowledge of normal human cardiac excitation stems from isolated heart or intraoperative mapping studies under nonphysiological conditions. Here, we use a noninvasive imaging modality (electrocardiographic imaging) to study normal activation and repolarization in intact unanesthetized healthy adults...