Irradiation-induced nasopharyngeal necrosis (INN) in newly diagnosed nasopharyngeal carcinoma treated by intensity-modulated radiation therapy: clinical characteristics and the influence of treatment strategies

• Published in: Radiation oncology (London, England) Vol. 17; no. 1; p. 13
• Main Authors: Xu, Yi, Liu, Yang, Wang, Zekun, Wang, Jingbo, Zhang, Jianghu, Chen, Xuesong, Wu, Runye, Liu, Qingfeng, Qu, Yuan, Wang, Kai, Huang, Xiaodong, Luo, Jingwei, Gao, Li, Xu, Guozhen, Zhang, Ye, Yi, Junlin
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 21.01.2022; BioMed Central; BMC
• Subjects: Adolescent; Adult; Aged; Anemia; Biomedical materials; Care and treatment; Carotid arteries; Chemotherapy; Complications and side effects; Debridement; Diseases; Endoscopy; Female; Gender; Headaches; Hemoglobin; Humans; Intensity-modulated radiation therapy; Irradiation; Irradiation-induced nasopharyngeal necrosis; Magnetic resonance imaging; Male; Medical prognosis; Middle Aged; Nasopharyngeal cancer; Nasopharyngeal carcinoma; Nasopharyngeal Carcinoma - radiotherapy; Nasopharyngeal Neoplasms - radiotherapy; Nasopharynx; Nasopharynx - pathology; Nasopharynx - radiation effects; Necrosis; Necrosis - diagnosis; Necrosis - etiology; Odors; Osteoradionecrosis; Patients; Primary nasopharyngeal carcinoma; Radiation; Radiation dosage; Radiation Injuries - etiology; Radiation therapy; Radiotherapy; Radiotherapy, Intensity-Modulated - adverse effects; Radiotherapy, Intensity-Modulated - methods; Regions; Regression analysis; Retrospective Studies; Survival; Throat cancer; Ulcers; Young Adult; China; Irradiation-induced nasopharyngeal necrosis; Intensity-modulated radiation therapy; Primary nasopharyngeal carcinoma

To define the clinical characteristics of irradiation-induced nasopharyngeal necrosis (INN) after intensity-modulated radiotherapy (IMRT) and identify the influence of treatment strategies on INN in primary nasopharyngeal carcinoma (NPC) patients. From 2008 to 2019, NPC patients pathologically diagn...